TRAINING PROGRAM IN DEVELOPMENTAL GENETICS

描述(由申请人提供)：此申请请求支持纽约大学的发育遗传学培训计划。该项目联合了纽约大学系统内两个不同实体的教师：纽约大学生物系和纽约大学医学院。发展遗传学培训计划的目标是加强和拓宽给予对发展遗传学有浓厚兴趣的学生的研究视角。发育遗传学已经成为生物学中最成功和最令人兴奋的学科之一。这一成功在很大程度上是由于实现了控制进化中看似分离的生物体发育的分子机制的保守程度。发育遗传学对于理解疾病基础的意义是显而易见的。该计划的一个长期目标是创造一个互动的环境，将发育遗传学基本原理的研究与对疾病影响的分子机制的理解结合起来。由于发育遗传学培训地点靠近一个充满活力的医疗中心，这一目标将得到加强。 该项目目前由来自纽约大学医学院和纽约大学生物系的19名教职员工组成，他们正在使用分子、细胞和遗传学方法研究各种生物(果蝇、线虫、小鼠、斑马鱼和酵母)的胚胎发育。这项计划得到了纽约大学医学院和纽约大学生物系的大力支持，在最先进的设施和招聘各级一流的教师方面。纽约大学医学院萨克勒研究生院和纽约大学生物系的开放研究生项目积极招生，吸引了高素质的研究生，包括代表不足的少数族裔学生。在目前的资助期间，有13名学生从该方案毕业，现在正在从事科学和医学方面的职业。目前，发育遗传学项目教职员工正在培训31名学生，其中4名学生得到了这笔培训补助金的支持。八个研究生培训职位(博士和医学博士/博士)都是被要求的。发展遗传学计划的培训包括：(A)在教员实验室严格追求发育遗传学，(B)在两个学期的课程中深入研究发育遗传学，其中发育生物学的问题在讲座和实验室部分讨论，(C)生物化学、遗传学和细胞生物学原理的广泛教育，(D)积极参加发展遗传学系列研讨会和期刊俱乐部(E)一年两次的发展遗传学学生座谈会以及研究生院、研究所和系“务虚会”，在那里学生必须展示他们的研究，以及(F)讨论小组和讲座，重点讨论科学中的道德行为问题和生物学毕业生的职业选择。

DESCRIPTION (provided by applicant): This application requests support for a Developmental Genetics Training Program at New York University. This program joins faculty from two different entities within the New York University system: the Department of Biology at New York University and the New York University School of Medicine. The goal of the Developmental Genetics Training Program is to enhance and broaden the research perspective given to students with strong interest in developmental genetics. Developmental genetics has become one of the most successful and exciting disciplines in biology. This success is largely due to the realization of the degree of conservation in the molecular mechanism that control development in evolutionary seemingly separate organisms. The implications of developmental genetics for the understanding of the basis of disease are evident. A long-term goal of this program is to seed an interactive environment that combines research in the basic principles of developmental genetics with understanding of the molecular mechanisms that are affected by disease. This goal will be enhanced by the proximity of the Developmental Genetics training site to a vibrant medical center. The program consists presently of a group of 19 faculty members from New York University School of Medicine and the Department of Biology, New York University who are using molecular, cellular, and genetic approaches to study embryonic development in a variety of organisms (Drosophila, C. elegans, mouse, zebrafish, and yeast). This program receives strong support from New York University School of Medicine and the Department of Biology at New York University in terms of state-of-the-art facilities and recruitment of first-rate faculty at all levels. Aggressive recruitment efforts by the open graduate programs at the Sackler School of Graduate Studies at New York University School of Medicine and the Department of Biology at New York University has lead to the attraction of high caliber graduate students, including underrepresented minority students. During the current funding period thirteen students graduated from the program and are now pursuing careers in science and medicine. At presently the Developmental Genetics Program faculty are training 31 students, four of them are supported by this training grant. Eight positions for graduate student training (Ph.D. and M.D./Ph.D.) are requested. Training in the Developmental Genetics Program includes (a) rigorous pursue in developmental genetics in the preceptors laboratory, (b) in depth studies in developmental genetics in a two semester course, in which questions in developmental biology are addressed in a lecture and laboratory part, (c) broad education in the principles of biochemistry, genetics, and cell biology, (d) active participation in the Developmental Genetics seminar series and journal clubs (e) a bi-annual Developmental Genetics Student Symposium as well as in graduate school, institute, and departmental "retreats", where students have to present their research, and (f) discussion groups and lectures focusing on issues of ethical conduct in science and career options for biology graduates.