Interdisciplinary Training in Virology and Gene Therapy

病毒学和基因治疗跨学科培训

基本信息

  • 批准号:
    7272814
  • 负责人:
  • 金额:
    $ 20.93万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2004
  • 资助国家:
    美国
  • 起止时间:
    2004-09-01 至 2009-08-31
  • 项目状态:
    已结题

项目摘要

DESCRIPTION (provided by applicant): Developments in virology have led to the advancement of several disciplines, including gene therapy. Gene therapy holds the promise for a variety of diseases. The key issue in gene therapy is the development of delivery vehicles. To fulfill the national need, the UCLA Virology and Gene Therapy Training Program aims to provide a unique and outstanding environment for predoctoral students pursuing research career in fields related to gene therapy. This Program will establish a solid training in fundamental virology and its applications in gene therapy. The research interests of our faculty encompass viral entry, viral gene expression regulation, replication of viral genome, cell biology during viral infection, viral particle assembly, viral carcinogenesis and viral immunology, as well as designing novel vectors and tracking viral vectors in vivo. With strong basic research programs on retroviruses, adenoviruses, SV40, hepatitis C, poliovirus, influenza virus and herpesviruses, our faculty has been and will be continuously developing viral vectors from these viruses and monitoring gene expression in vivo using non-invasive imaging technologies. The trainees will be exposed to clinical and diagnostic issues during their training to assist the therapeutic applications of their research projects. This bridge in training environment will enhance the translation from basic science to clinical application in gene therapy. The training program constitutes 1) original research work with one of our faculty; 2) formal course work which provides comprehensive background on virology, gene therapy, and imaging; and 3) regular research conferences and seminars, presented by invited guest speakers, faculty members and trainees. The training committee will select trainees via a competitive process. Appointment is renewable for two additional years with satisfactory progress. At UCLA, this rigorous training program with emphasis on vertical integration of basic sciences and therapeutic applications will produce scientists required for long-term development of gene therapy.
描述(由申请人提供):病毒学的发展导致了几个学科的进步,包括基因治疗。基因疗法有望治疗多种疾病。基因治疗的关键问题是载体的开发。为了满足国家的需要,UCLA病毒学和基因治疗培训计划旨在为从事基因治疗相关领域研究的博士前学生提供一个独特而出色的环境。该计划将建立一个坚实的基础病毒学及其在基因治疗中的应用培训。我们的教师的研究兴趣包括病毒进入,病毒基因表达调控,病毒基因组的复制,病毒感染过程中的细胞生物学,病毒颗粒组装,病毒致癌和病毒免疫学,以及设计新型载体和体内追踪病毒载体。凭借对逆转录病毒,腺病毒,SV 40,丙型肝炎,脊髓灰质炎病毒,流感病毒和疱疹病毒的强大基础研究计划,我们的教师已经并将继续从这些病毒中开发病毒载体,并使用非侵入性成像技术监测体内基因表达。学员将在培训期间接触临床和诊断问题,以协助其研究项目的治疗应用。这种培训环境中的桥梁将促进基因治疗从基础科学到临床应用的转化。培训计划包括:1)与我们的教师之一进行原创研究工作; 2)正式课程工作,提供病毒学,基因治疗和成像的全面背景; 3)定期研究会议和研讨会,由特邀演讲嘉宾,教师和学员介绍。培训委员会将通过竞争程序挑选受训人员。如有令人满意的进展,可连任两年。在加州大学洛杉矶分校,这个严格的培训计划,重点是基础科学和治疗应用的垂直整合,将产生基因治疗长期发展所需的科学家。

项目成果

期刊论文数量(0)
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科研奖励数量(0)
会议论文数量(0)
专利数量(0)

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REN SUN其他文献

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{{ truncateString('REN SUN', 18)}}的其他基金

Structure-guided development of chemical inhibitors against Kaposi’s sarcoma-associated herpesvirus (KSHV)
针对卡波西肉瘤相关疱疹病毒 (KSHV) 的化学抑制剂的结构引导开发
  • 批准号:
    9791594
  • 财政年份:
    2019
  • 资助金额:
    $ 20.93万
  • 项目类别:
Atomic structure of Kaposi's sarcoma-associated herpesvirus capsid
卡波西肉瘤相关疱疹病毒衣壳的原子结构
  • 批准号:
    9185965
  • 财政年份:
    2015
  • 资助金额:
    $ 20.93万
  • 项目类别:
Innate Immune Responses and Vaccines Against Tumor-Associated Herpesviruses
先天免疫反应和针对肿瘤相关疱疹病毒的疫苗
  • 批准号:
    8930083
  • 财政年份:
    2014
  • 资助金额:
    $ 20.93万
  • 项目类别:
Innate Immune Responses and Vaccines Against Tumor-Associated Herpesviruses
先天免疫反应和针对肿瘤相关疱疹病毒的疫苗
  • 批准号:
    8659738
  • 财政年份:
    2014
  • 资助金额:
    $ 20.93万
  • 项目类别:
Fitness Profile of HIV-1 Genome with Host Cofactor Selection Pressure
HIV-1 基因组与宿主辅因子选择压力的适应度概况
  • 批准号:
    8731701
  • 财政年份:
    2014
  • 资助金额:
    $ 20.93万
  • 项目类别:
Innate Immune Responses and Vaccines Against Tumor-Associated Herpesviruses
先天免疫反应和针对肿瘤相关疱疹病毒的疫苗
  • 批准号:
    9124751
  • 财政年份:
    2014
  • 资助金额:
    $ 20.93万
  • 项目类别:
Innate Immune Responses and Vaccines Against Tumor-Associated Herpesviruses
先天免疫反应和针对肿瘤相关疱疹病毒的疫苗
  • 批准号:
    9341079
  • 财政年份:
    2014
  • 资助金额:
    $ 20.93万
  • 项目类别:
Functional Profiles of Hepatitis C Virus Genome at Single Nucleotide Resolution
单核苷酸分辨率丙型肝炎病毒基因组的功能谱
  • 批准号:
    8731700
  • 财政年份:
    2014
  • 资助金额:
    $ 20.93万
  • 项目类别:
Administrative Service
行政服务
  • 批准号:
    8660817
  • 财政年份:
    2014
  • 资助金额:
    $ 20.93万
  • 项目类别:
In vivo Interactions Between a Gamma-Herpesvirus and Innate Immune Responses
γ-疱疹病毒与先天免疫反应之间的体内相互作用
  • 批准号:
    8660816
  • 财政年份:
    2014
  • 资助金额:
    $ 20.93万
  • 项目类别:

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病毒学和基因治疗博士培训项目
  • 批准号:
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  • 财政年份:
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病毒学和基因治疗跨学科培训
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病毒学和基因治疗跨学科培训
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    6937250
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病毒学和基因治疗跨学科培训
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