PhD Training Program in Virology and Gene Therapy

项目摘要 生命科学中统一的科学原理继续在病毒系统中被发现。基因治疗和 溶瘤病毒疗法依赖于病毒载体。意识到对基础病毒学的深刻理解是 基因治疗发展的需要导致了病毒学和基因治疗(VGT)的建立 梅奥研究生院2004年的轨迹。博士培训利用基础研究的力量和强大的 梅奥诊所的翻译基础设施。培训在22名VGT教职员工的实验室进行。 9名来自分子医学系，3名来自传染病科，以及 其他人来自九个不同的部门和项目。他们因在病毒研究方面的领先地位而团结在一起， 媒介、人类疾病的机制、癌症治疗和基因治疗。VGT的受欢迎程度部分是基于 关于其在病毒学以及病毒和基因疗法翻译方面的独特培训机会。在.期间 在论文的整个时间里，学生们参与了包括日记在内的一系列纲领性活动 俱乐部、系列研讨会、年度静修和国家科学会议。VGT赛道的要求 符合梅奥研究生院的一般要求。国立卫生研究院在第四年为三名学员提供支持 他们的论文中有5个将允许扩展这个成功和创新的项目。

Project Summary Unifying scientific principles in the life sciences continue to be discovered in viral systems. Gene therapy and oncolytic virotherapy depend on viral vectors. Awareness that a deep understanding of basic virology is necessary for the development of gene therapy led to the foundation of the Virology and Gene Therapy (VGT) track of Mayo Graduate School in 2004. Ph.D. training leverages the strength of basic research and the robust translational infrastructure at Mayo Clinic. Training is performed in the laboratories of 22 VGT faculty members. Nine are from the Department of Molecular Medicine, three from the Division of Infectious Diseases, and the others from nine different departments and programs. They are united by leadership in research on viruses, vectors, mechanisms of human disease, cancer treatment, and gene therapy. VGT popularity is based in part on its unique training opportunities in both virology and the translation of viral and gene therapeutics. During the entire time of their thesis the students engage in a full array of programmatic activities including journal clubs, seminar series, an annual retreat and national scientific meetings. Requirements for the VGT track conform to the general requirements of the Mayo Graduate School. NIH support of three trainees in years 4 and 5 of their thesis would allow expanding this successful and innovative program.