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PhD Training Program in Virology and Gene Therapy

病毒学和基因治疗博士培训项目

基本信息

批准号：
10415994
负责人：
ROBERTO B. CATTANEO
金额：
$ 14.68万
依托单位：
MAYO CLINIC ROCHESTER
依托单位国家：
美国
项目类别：
财政年份：
2018
资助国家：
美国
起止时间：
2018-08-15 至 2023-07-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10415994
关键词：
Doctor of Philosophy Training Programs gene therapy virology

项目摘要

Project Summary Unifying scientific principles in the life sciences continue to be discovered in viral systems. Gene therapy and oncolytic virotherapy depend on viral vectors. Awareness that a deep understanding of basic virology is necessary for the development of gene therapy led to the foundation of the Virology and Gene Therapy (VGT) track of Mayo Graduate School in 2004. Ph.D. training leverages the strength of basic research and the robust translational infrastructure at Mayo Clinic. Training is performed in the laboratories of 22 VGT faculty members. Nine are from the Department of Molecular Medicine, three from the Division of Infectious Diseases, and the others from nine different departments and programs. They are united by leadership in research on viruses, vectors, mechanisms of human disease, cancer treatment, and gene therapy. VGT popularity is based in part on its unique training opportunities in both virology and the translation of viral and gene therapeutics. During the entire time of their thesis the students engage in a full array of programmatic activities including journal clubs, seminar series, an annual retreat and national scientific meetings. Requirements for the VGT track conform to the general requirements of the Mayo Graduate School. NIH support of three trainees in years 4 and 5 of their thesis would allow expanding this successful and innovative program.

项目概要在病毒系统中不断发现生命科学中统一的科学原理。基因治疗和溶瘤病毒疗法依赖于病毒载体。意识到对基础病毒学的深刻理解是基因治疗发展所必需的，导致了病毒学和基因治疗（VGT）的基础 2004年获得梅奥研究生院博士学位。培训利用基础研究的力量和强大的梅奥诊所的转化基础设施。培训在 22 名 VGT 教员的实验室中进行。九名来自分子医学系，三名来自传染病科，以及其他人来自九个不同的部门和项目。他们因在病毒研究方面的领导地位而团结在一起，载体、人类疾病机制、癌症治疗和基因治疗。 VGT 受欢迎程度部分基于因其在病毒学以及病毒和基因疗法翻译方面独特的培训机会。期间在论文的整个过程中，学生们参与了一系列的计划活动，包括日记俱乐部、研讨会系列、年度静修会和全国科学会议。 VGT 赛道的要求符合梅奥研究生院的一般要求。 NIH 在第 4 年为三名实习生提供支持他们的 5 篇论文将扩展这一成功且创新的项目。