Exploiting organoboron chemistry to prepare saturated heterocycles

利用有机硼化学制备饱和杂环

• 批准号: 2902215
• 金额: --
• 依托单位: University of Sheffield
• 依托单位国家: 英国
• 项目类别: Studentship
• 财政年份: 2022
• 资助国家: 英国
• 起止时间: 2022 至 无数据
• 项目状态: 未结题
• 来源: https://gtr.ukri.org/projects?ref=studentship-2902215
• 关键词: Exploiting; organoboron; chemistry; prepare; saturated

The project will investigate boronate rearrangement reactions, ultimately targeting alkyl boronic ester heterocycles. There are few of these known, unlike their aryl counterparts. Simple synthesis methods are sought-after as these heterocycles could have potentially wide usage in the pharmaceutical industry, serving as building blocks for drug molecules via important transformations such as the hugely popular Suzuki-Miyaura coupling

该项目将研究硼酸酯重排反应，最终目标是烷基硼酸酯杂环。很少有人知道这些，不像他们的芳基对应物。简单的合成方法是抢手的，因为这些杂环可能在制药工业中具有潜在的广泛用途，通过重要的转化，如非常受欢迎的Suzuki-Miyaura偶联，