The Impact of Lymphedema on Overall and Local Functioning
The Impact of Lymphedema on Overall and Local Functioning
批准号:
7283965
负责人:
MARYLIN J DODD
金额:
$22.43万
依托单位国家:
美国
项目类别:
财政年份:
2006
资助国家:
美国
项目状态:
已结题
起止时间:
2006-09-05 至 2009-06-30
关键词:
AffectAftercareAppearanceArticular Range of MotionAttenuatedBiolectric ImpedanceCancer SurvivorClinicalClinical ResearchConditionConsensusDetectionDiagnosisDiscriminationDistressEarly treatmentFemale Breast CarcinomaFrequenciesFunctional disorderFutureHandHealth PersonnelHourImpairmentIncidenceInterventionIntervention StudiesLaboratoriesLimb structureLiquid substanceLiteratureLocalizedLymphedemaManualsMeasurementMeasuresMethodsMorbidity - disease rateMotionOperative Surgical ProceduresPatientsPhysical FitnessPhysical FunctionPurposeQuality of lifeQuestionnairesRadiation therapyRangeRange of motion exerciseRecording of previous eventsReportingRiskSamplingShoulderSpectrum AnalysisStagingStimulusSymptomsTechniquesTestingTimeUpper ExtremityUpper armWaterWomancancer surgeryclinical Diagnosisexperienceextracellularfitnessgraspimpressionmalignant breast neoplasmoncology
中文摘要
DESCRIPTION (provided by applicant): Arm lymphedema may arise at any time after breast cancer surgery and/or radiation therapy. A wide range in incidence has been reported in the literature, but there is general consensus for 20-28%. Lymphedema can result in notable morbidity e.g., distress as to appearance, discomfort, and dysfunction. The overall hypothesis of the proposed study is that lymphedema detrimentally affects local functioning of the upper extremity of the affected arm, and consequently affects the overall health-related functioning in breast cancer survivors. The purposes/aims of this cross sectional correlational study are: 1. to determine the relationship between degree of lymphedema and local upper extremity (hand, arm, shoulder) functioning; 2. to determine the relationship between degree of lymphedema, lymphedema-associated symptoms, localized upper extremity functioning, and overall health-related functioning; 3. to determine the relationship between degree of lymphedema, lymphedema-associated symptoms, localized upper extremity functioning overall health-related functioning, and quality of life. The sample will include 300 women who are breast cancer survivors. The entire testing/measurement session will take 3-4 hours in the General Clinical Research Center at UCSF. The session will include: measurement of lymphedema using bioelectrical impedance spectroscopy, specifically, multiple frequency bioelectrical analysis (MFBIA), local upper extremity functioning, and overall health-related functioning tests, as well as questionnaires related to lymphedema-associated symptoms and quality of life. Correlational analyses are planned to answer the aims of this study. By using the MFBIA measurement and carefully detailing the local upper extremity dysfunction and overall functioning of these women, as well as the symptom experience and their quality of life, the study will make an important contribution to our understanding of lymphedema, and will inform future intervention studies.
英文摘要
DESCRIPTION (provided by applicant): Arm lymphedema may arise at any time after breast cancer surgery and/or radiation therapy. A wide range in incidence has been reported in the literature, but there is general consensus for 20-28%. Lymphedema can result in notable morbidity e.g., distress as to appearance, discomfort, and dysfunction. The overall hypothesis of the proposed study is that lymphedema detrimentally affects local functioning of the upper extremity of the affected arm, and consequently affects the overall health-related functioning in breast cancer survivors. The purposes/aims of this cross sectional correlational study are: 1. to determine the relationship between degree of lymphedema and local upper extremity (hand, arm, shoulder) functioning; 2. to determine the relationship between degree of lymphedema, lymphedema-associated symptoms, localized upper extremity functioning, and overall health-related functioning; 3. to determine the relationship between degree of lymphedema, lymphedema-associated symptoms, localized upper extremity functioning overall health-related functioning, and quality of life. The sample will include 300 women who are breast cancer survivors. The entire testing/measurement session will take 3-4 hours in the General Clinical Research Center at UCSF. The session will include: measurement of lymphedema using bioelectrical impedance spectroscopy, specifically, multiple frequency bioelectrical analysis (MFBIA), local upper extremity functioning, and overall health-related functioning tests, as well as questionnaires related to lymphedema-associated symptoms and quality of life. Correlational analyses are planned to answer the aims of this study. By using the MFBIA measurement and carefully detailing the local upper extremity dysfunction and overall functioning of these women, as well as the symptom experience and their quality of life, the study will make an important contribution to our understanding of lymphedema, and will inform future intervention studies.
期刊论文(3)
专著(0)
科研奖励(0)
会议论文
DOI:
10.1016/j.apmr.2010.11.017
发表时间:
2011-04
期刊:
ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION
影响因子:
4.3
作者:
[Smoot, Betty J., Wong, Josephine F., Dodd, Marylin J.]
通讯作者:
Dodd, Marylin J.
Cardiorespiratory Fitness in Women with and without Lymphedema following Breast Cancer Treatment.
乳腺癌治疗后患有和不患有淋巴水肿的女性的心肺健康。
DOI:
10.5539/cco.v1n1p21
发表时间:
2012
期刊:
Cancer and clinical oncology
影响因子:
--
作者:
[Smoot,Betty, Johnson,Morgan, DudaJ,John, Krasnoff,Joanne, Dodd,Marylin]
通讯作者:
Dodd,Marylin
The Impact of Lymphedema on Overall and Local Functioning
-
批准号:7129989
-
项目类别:
-
资助金额:$19.19万
-
财政年份:2006
-
负责人:MARYLIN J DODD
-
依托单位:
Exercise: An Intervention for Fatigue in Cancer Patients
-
批准号:6972232
-
项目类别:
-
资助金额:$2.59万
-
财政年份:2004
-
负责人:MARYLIN J DODD
-
依托单位:
Management of Mucositis with GM-CSF
-
批准号:7281616
-
项目类别:
-
资助金额:$100.07万
-
财政年份:2003
-
负责人:MARYLIN J DODD
-
依托单位:
Management of Mucositis with GM-CSF
-
批准号:7490659
-
项目类别:
-
资助金额:$45.67万
-
财政年份:2003
-
负责人:MARYLIN J DODD
-
依托单位:
Management of Mucositis with GM-CSF
-
批准号:6938547
-
项目类别:
-
资助金额:$88.21万
-
财政年份:2003
-
负责人:MARYLIN J DODD
-
依托单位:
Management of Mucositis with GM-CSF
-
批准号:7125195
-
项目类别:
-
资助金额:$15.02万
-
财政年份:2003
-
负责人:MARYLIN J DODD
-
依托单位:
Management of Mucositis with GM-CSF
-
批准号:6767374
-
项目类别:
-
资助金额:$78.35万
-
财政年份:2003
-
负责人:MARYLIN J DODD
-
依托单位:
Management of Mucositis with GM-CSF
-
批准号:6800485
-
项目类别:
-
资助金额:$79.06万
-
财政年份:2003
-
负责人:MARYLIN J DODD
-
依托单位:
EXERCISE--AN INTERVENTION FOR FATIGUE IN CANCER PATIENTS
-
批准号:6514200
-
项目类别:
-
资助金额:$60.56万
-
财政年份:1999
-
负责人:MARYLIN J DODD
-
依托单位:
EXERCISE--AN INTERVENTION FOR FATIGUE IN CANCER PATIENTS
-
批准号:2822836
-
项目类别:
-
资助金额:$36.33万
-
财政年份:1999
-
负责人:MARYLIN J DODD
-
依托单位:
EXERCISE--AN INTERVENTION FOR FATIGUE IN CANCER PATIENTS
-
批准号:6164323
-
项目类别:
-
资助金额:$58.83万
-
财政年份:1999
-
负责人:MARYLIN J DODD
-
依托单位:
EXERCISE--AN INTERVENTION FOR FATIGUE IN CANCER PATIENTS
-
批准号:6362729
-
项目类别:
-
资助金额:$59.43万
-
财政年份:1999
-
负责人:MARYLIN J DODD
-
依托单位:
EXERCISE--AN INTERVENTION FOR FATIGUE IN CANCER PATIENTS
-
批准号:6633524
-
项目类别:
-
资助金额:$56.64万
-
财政年份:1999
-
负责人:MARYLIN J DODD
-
依托单位:
RESEARCH CENTER FOR SYMPTOM MANAGEMENT
-
批准号:2257950
-
项目类别:
-
资助金额:$30.82万
-
财政年份:1994
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负责人:MARYLIN J DODD
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依托单位:
RESEARCH CENTER FOR SYMPTOM MANAGEMENT
-
批准号:2460415
-
项目类别:
-
资助金额:$33.59万
-
财政年份:1994
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负责人:MARYLIN J DODD
-
依托单位:
RESEARCH CENTER FOR SYMPTOM MANAGEMENT
-
批准号:2257951
-
项目类别:
-
资助金额:$32.29万
-
财政年份:1994
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负责人:MARYLIN J DODD
-
依托单位:
RESEARCH CENTER FOR SYMPTOM MANAGEMENT
-
批准号:2750728
-
项目类别:
-
资助金额:$35.04万
-
财政年份:1994
-
负责人:MARYLIN J DODD
-
依托单位:
RESEARCH CENTER FOR SYMPTOM MANAGEMENT
-
批准号:2257949
-
项目类别:
-
资助金额:$29.6万
-
财政年份:1994
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负责人:MARYLIN J DODD
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依托单位:
SELF CARE INTERVENTION TO DECREASE MUCOSITIS MORBIDITY
-
批准号:2096689
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项目类别:
-
资助金额:$36.65万
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财政年份:1992
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负责人:MARYLIN J DODD
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依托单位:
SELF-CARE INTERVENTION TO DECREASE MUCOSITIS MORBIDITY
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批准号:3200051
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项目类别:
-
资助金额:$41.83万
-
财政年份:1992
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负责人:MARYLIN J DODD
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依托单位:
海外基金