权益分类	功能权益	普通用户	{{item.name}}会员
{{category.name}}	{{benefitItem.name}}

The Impact of Lymphedema on Overall and Local Functioning

淋巴水肿对整体和局部功能的影响

基本信息

批准号：
7283965
负责人：
MARYLIN J DODD
金额：
$ 22.43万
依托单位：
UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
依托单位国家：
美国
项目类别：
财政年份：
2006
资助国家：
美国
起止时间：
2006-09-05 至 2009-06-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/7283965
关键词：
Affect Aftercare Appearance Articular Range of Motion Attenuated Biolectric Impedance Cancer Survivor Clinical Clinical Research Condition Consensus Detection Diagnosis Discrimination Distress Early treatment Female Breast Carcinoma Frequencies Functional disorder Future Hand Health Personnel Hour Impairment Incidence Intervention Intervention Studies Laboratories Limb structure Liquid substance Literature Localized Lymphedema Manuals Measurement Measures Methods Morbidity - disease rate Motion Operative Surgical Procedures Patients Physical Fitness Physical Function Purpose Quality of life Questionnaires Radiation therapy Range Range of motion exercise Recording of previous events Reporting Risk Sampling Shoulder Spectrum Analysis Staging Stimulus Symptoms Techniques Testing Time Upper Extremity Upper arm Water Woman cancer surgery clinical Diagnosis experience extracellular fitness grasp impression malignant breast neoplasm oncology

项目摘要

DESCRIPTION (provided by applicant): Arm lymphedema may arise at any time after breast cancer surgery and/or radiation therapy. A wide range in incidence has been reported in the literature, but there is general consensus for 20-28%. Lymphedema can result in notable morbidity e.g., distress as to appearance, discomfort, and dysfunction. The overall hypothesis of the proposed study is that lymphedema detrimentally affects local functioning of the upper extremity of the affected arm, and consequently affects the overall health-related functioning in breast cancer survivors. The purposes/aims of this cross sectional correlational study are: 1. to determine the relationship between degree of lymphedema and local upper extremity (hand, arm, shoulder) functioning; 2. to determine the relationship between degree of lymphedema, lymphedema-associated symptoms, localized upper extremity functioning, and overall health-related functioning; 3. to determine the relationship between degree of lymphedema, lymphedema-associated symptoms, localized upper extremity functioning overall health-related functioning, and quality of life. The sample will include 300 women who are breast cancer survivors. The entire testing/measurement session will take 3-4 hours in the General Clinical Research Center at UCSF. The session will include: measurement of lymphedema using bioelectrical impedance spectroscopy, specifically, multiple frequency bioelectrical analysis (MFBIA), local upper extremity functioning, and overall health-related functioning tests, as well as questionnaires related to lymphedema-associated symptoms and quality of life. Correlational analyses are planned to answer the aims of this study. By using the MFBIA measurement and carefully detailing the local upper extremity dysfunction and overall functioning of these women, as well as the symptom experience and their quality of life, the study will make an important contribution to our understanding of lymphedema, and will inform future intervention studies.