Medical Scientist Training Program at University of Texas Southwestern Med Ctr

描述（由申请人提供）：这是UT西南部MSTP的更新申请，该培训MD/PhD医生科学家将实验科学的原则应用于人类疾病的基本问题，并将这种理解转化为下一代有效的患者护理。该计划正在进入NIH连续资助的第25个年头。在过去的5年资助期内，UT西南MSTP通过将其申请流程转换为国家AMCAS系统，将申请数量增加了2.5至3倍。候选人提供录取该计划目前强大的学术证书（平均。GPA = 3.77，平均MCAT = 35.6），入学机会扩大到约10%的申请人。在最后五个班中，每个班都有10至16名学生报名参加该方案，目前有97名MSTP学生。过去五个毕业班的平均学位时间为8.3年。新颁布的课程修改将把获得学位的平均时间缩短到8年以下。MSTP学生通常完成3个研究轮换和2年的医学院，然后开始论文研究。在研究期间，学生参加研究生课程，通过资格考试，并在研究生院250名教师之一的实验室工作。MSTP导师资金充足（平均。140万美元/PI），通常监督与医学相关的基础科学项目的研究。MSTP学生选择导师在全方位的教师轮换/博士研究，并完成他们的博士研究与生产力的强大记录，平均生产4出版物。计划毕业生最经常在优秀的机构进行临床住院医师（上一个奖项学期为35/37）。MSTP的共同主任都是活跃的医生-科学家，在研究和临床医学方面有着杰出的记录。共同董事建立计划政策，并通过MD/博士路径与副院长一起引导学生，也是UT西南部教师的活跃科学家，负责管理计划管理。与联合董事和副院长一起，一个由19名成员组成的指导委员会作为招生委员会运作，并帮助制定计划政策。在其24年来，MSTP已经毕业了124 MSTP资助的学生和职业成果支持该计划的原始NIH任务：89%的毕业生谁是在独立的职位正在做医学研究学术医学（86%）或制药行业的职位（3%）。

DESCRIPTION (provided by applicant): This is a renewal application for the MSTP at UT Southwestern which trains MD/PhD physician-scientists to bring the principles of experimental science to bear on fundamental problems in human disease and to translate that understanding into the next generation of effective patient care. The Program is entering its 25th year of continuous NIH funding. During the previous 5-year funding period, the UT Southwestern MSTP increased the number of applications by 2.5- to 3-fold by converting its application process to the national AMCAS system. Candidates offered admission to the Program present strong academic credentials (Avg. GPA = 3.77, Avg. MCAT = 35.6) and offers of admission are extended to ~10% of applicants. Between 10 and 16 students enrolled in the Program in each of the last five classes and there are currently 97 MSTP students. The average time to degree for the last five graduating classes was 8.3 years. Newly enacted curriculum modifications will reduce the average time to degree to less than 8 years. MSTP students typically complete 3 research rotations and 2 years of medical school before embarking on dissertation research. During the research years, students take graduate courses, pass a qualifying exam and work in the lab of one of the ~250 faculty members on the Graduate School faculty. MSTP mentors are well-funded (avg. $1.4M/PI) and typically oversee research in medically-relevant basic science projects. MSTP students select mentors for rotations/PhD research across the full spectrum of faculty and complete their PhD research with strong records of productivity, producing an average of 4 publications. Program graduates most often move on to clinical residencies (35/37 in last award term) at excellent institutions. The MSTP co-Directors are active physician-scientists with distinguished records in research and clinical medicine. The co-Directors establish Program policy and guide students through the MD/PhD path together with an Associate Dean, also an active scientist on UT Southwestern faculty, who manages program administration. Together with the co-Directors and Assoc. Dean, a 19 member Steering Committee operates as an admissions committee and helps set Program policies. In its 24 years, the MSTP has graduated 124 MSTP-funded students and career outcomes support the original NIH mandate for the Program: 89% of graduates who are in independent positions are doing medical research in academic medicine (86%) or pharmaceutical industry positions (3%).