Medical Scientist Training Program at University of Texas Southwestern Med Ctr

描述(由申请人提供)：这是德克萨斯大学西南分校MSTP的续签申请，该计划培训医学博士/博士内科科学家将实验科学的原理应用于人类疾病的基本问题，并将这种理解转化为下一代有效的患者护理。该计划进入了NIH连续资助的第25个年头。在之前的5年资助期内，德克萨斯大学西南MSTP通过将其申请程序转换为国家AMCAS系统，使申请数量增加了2.5倍至3倍。提供该项目录取的应聘者提供优秀的学术资历(平均GPA=3.77，平均MCAT=35.6)，录取机会扩大到约10%的申请者。在过去的五个班级中，每个班都有10到16名学生报名参加该计划，目前有97名MSTP学生。最近五届毕业生获得学位的平均时间为8.3年。新颁布的课程修订将把获得学位的平均时间减少到8年以下。MSTP的学生在开始论文研究之前，通常要完成三次研究轮换和两年的医学院学习。在研究期间，学生们参加研究生课程，通过资格考试，并在研究生院教职员工中约250名教职员工的实验室工作。MSTP导师资金充足(平均140万美元/PI)，通常监督与医学相关的基础科学项目的研究。MSTP的学生为所有教师的轮换/博士研究选择导师，并以出色的生产力记录完成他们的博士研究，平均出版4本出版物。该项目的毕业生大多会转到优秀机构的临床实习(上一届获奖项目中有35/37)。MSTP联席主任是活跃的内科科学家，在研究和临床医学方面有杰出的记录。联席主任制定项目政策，并与一名副院长一起指导学生通过医学/博士课程，副院长也是德克萨斯大学西南学院的活跃科学家，负责管理项目管理。与联席董事和ASSOC一起。Dean是一个由19名成员组成的指导委员会，作为招生委员会运作，并帮助制定计划政策。在其24年的时间里，MSTP资助的124名学生毕业，职业结果支持了NIH最初对该计划的要求：89%的独立职位毕业生从事学术医学(86%)或制药行业职位(3%)的医学研究。

DESCRIPTION (provided by applicant): This is a renewal application for the MSTP at UT Southwestern which trains MD/PhD physician-scientists to bring the principles of experimental science to bear on fundamental problems in human disease and to translate that understanding into the next generation of effective patient care. The Program is entering its 25th year of continuous NIH funding. During the previous 5-year funding period, the UT Southwestern MSTP increased the number of applications by 2.5- to 3-fold by converting its application process to the national AMCAS system. Candidates offered admission to the Program present strong academic credentials (Avg. GPA = 3.77, Avg. MCAT = 35.6) and offers of admission are extended to ~10% of applicants. Between 10 and 16 students enrolled in the Program in each of the last five classes and there are currently 97 MSTP students. The average time to degree for the last five graduating classes was 8.3 years. Newly enacted curriculum modifications will reduce the average time to degree to less than 8 years. MSTP students typically complete 3 research rotations and 2 years of medical school before embarking on dissertation research. During the research years, students take graduate courses, pass a qualifying exam and work in the lab of one of the ~250 faculty members on the Graduate School faculty. MSTP mentors are well-funded (avg. $1.4M/PI) and typically oversee research in medically-relevant basic science projects. MSTP students select mentors for rotations/PhD research across the full spectrum of faculty and complete their PhD research with strong records of productivity, producing an average of 4 publications. Program graduates most often move on to clinical residencies (35/37 in last award term) at excellent institutions. The MSTP co-Directors are active physician-scientists with distinguished records in research and clinical medicine. The co-Directors establish Program policy and guide students through the MD/PhD path together with an Associate Dean, also an active scientist on UT Southwestern faculty, who manages program administration. Together with the co-Directors and Assoc. Dean, a 19 member Steering Committee operates as an admissions committee and helps set Program policies. In its 24 years, the MSTP has graduated 124 MSTP-funded students and career outcomes support the original NIH mandate for the Program: 89% of graduates who are in independent positions are doing medical research in academic medicine (86%) or pharmaceutical industry positions (3%).