Exploration of Therapeutic Strategies in Mar

3月治疗策略探索

• 批准号: 7460912
• 负责人: Harry C., III Dietz
• 金额: $ 24.22万
• 依托单位: UNIV OF MED/DENT NJ-R W JOHNSON MED SCH
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-07-01 至 2009-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7460912
• 关键词: Adrenergic beta-Antagonists; Alleles; Alveolar; Aneurysm; Angiotensin II Type 1 Receptor Blockers; Aorta; Basic Science; Biological; Cardiac; Cardiopulmonary; Cardiovascular system; Caring; Characteristics; Clinical; Connective Tissue Diseases; Cytokine Activation; Cytokine Signaling; Data; Development; Disease; Disruption; Distal; Dominant-Negative Mutation; Effectiveness; End Point; Enzymes; Evaluation; Event; Exons; FBN1; Failure; Family member; Fatty acid glycerol esters; Genes; Genetic; Growth; Histologic; Homeostasis; Human; Inflammation; Investigation; Knowledge; Losartan; Lung; MADH4 gene; MADH6 gene; MADH7 gene; Marfan Syndrome; Microfibrils; Molecular; Mouse Strains; Mus; Muscle; Muscle Development; Mutation; Myocardium; Natural regeneration; Parabiosis; Pathogenesis; Pathway interactions; Patients; Performance; Phase; Phenotype; Physiological; Planet Mars; Play; Population; Predisposition; Process; Protein Overexpression; Range; Reducing Agents; Regulation; Relative (related person); Research; Role; Series; Severities; Signal Transduction; Standards of Weights and Measures; Stress; Testing; Therapeutic; Time; Tissues; Transforming Growth Factor beta; Translating; Treatment Efficacy; Treatment Protocols; base; bone; cytokine; drug development; extracellular; fibrillin; genetic manipulation; hemodynamics; in vivo; insight; loss of function; member; mouse model; myostatin; neutralizing antibody; novel; novel therapeutics; prevent; programs; receptor; research study