NSABP Participating Sites

NSABP 参与地点

• 批准号: 7220608
• 负责人: JENNY C-N CHANG
• 金额: $ 6.65万
• 依托单位: BAYLOR COLLEGE OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-04-10 至 2012-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7220608
• 关键词: Aftercare; Biological Markers; Biology; Breast; Breast Cancer Prevention Trial; Breast Cancer Prognostic Factor; Caring; Clinic; Clinical; Clinical Services; Clinical Trials; Collaborations; Complement; County Hospitals; Disadvantaged; Disease; ERBB2 gene; Gene Abnormality; Gene Expression Profile; General Hospitals; Genomics; Goals; Grant; Hospitals; Investigation; Mammary Neoplasms; Medicine; Methodist Church; Minority; National Surgical Adjuvant Breast and Bowel Project; Nature; Neoadjuvant Therapy; Numbers; Outcome; Patients; Pilot Projects; Population; Prediction of Response to Therapy; Principal Investigator; Prognostic Factor; Prognostic Marker; Publications; Rate; Recruitment Activity; Reproduction spores; Research; Research Infrastructure; Research Personnel; Scientist; Site; Southwest Oncology Group; TP53 gene; Tamoxifen; Technology; Time; Tissues; Translational Research; Trastuzumab; Tumor Biology; Validation; Woman; Women' s Group; Work; base; cDNA Arrays; chemotherapy; college; density; experience; hormone therapy; improved; malignant breast neoplasm; member; multidisciplinary; oncology; research study; response; treatment trial

DESCRIPTION (provided by applicant): The Breast Care Center at Baylor College of Medicine is a broad based, multidisciplinary organization composed of investigators dedicated to exploring the biology of breast cancer, and through a better understanding of this biology, to improving cure rates and treatments for the disease. The strengths of the Center will complement, reinforce, and extend the goals of the NSABP. Over the past five years, we have established a clinical presence and infrastructure at Baylor College of Medicine which facilitates the recruitment of a wide variety of patients onto treatment studies. Along with our Breast Care Center, established in collaboration with The Methodist Hospital, we have also been successful in establishing a dedicated breast oncology clinic at Ben Taub General Hospital, a county hospital which serves a large number of disadvantaged and minority women with breast cancer, and are successfully recruiting from this population. Center investigators have developed a considerable expertise over the past twenty-five years in molecular markers of prognosis and prediction of response to therapy, and most recently have extended their efforts into high through-put genomic technologies. Through the combined strength of a busy, high volume clinical service and established clinical trial infrastructure, along with scientists and clinicians deeply experienced in translational and molecular marker research, we will be able to make a unique contribution towards the NSABP's goal of optimum, individualized treatment for all women with breast cancer.

描述（由申请人提供）：贝勒医学院的乳房护理中心是一个基础广泛的多学科组织，由致力于探索乳腺癌生物学的研究人员组成，并通过更好地了解这种生物学，提高治愈率和疾病的治疗。该中心的优势将补充、加强和扩大国家生物安保战略的目标。在过去的五年中，我们已经在贝勒医学院建立了临床存在和基础设施，这有助于招募各种各样的患者进行治疗研究。沿着我们与卫理公会医院合作建立的乳房护理中心，我们还成功地在Ben Taub综合医院建立了一个专门的乳腺肿瘤诊所，该医院是一家县医院，为大量患有乳腺癌的弱势和少数民族妇女提供服务，并成功地从这一人群中招募人员。在过去的25年里，中心的研究人员在预后和治疗反应预测的分子标志物方面积累了相当丰富的专业知识，最近他们将努力扩展到高通量基因组技术。通过结合忙碌、大量的临床服务和已建立的临床试验基础设施，沿着在转化和分子标记物研究方面经验丰富的科学家和临床医生，我们将能够为NSABP为所有乳腺癌女性提供最佳、个性化治疗的目标做出独特的贡献。