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中文摘要
翻译
贝勒医学院乳房护理中心是一个基础广泛的多学科组织 由致力于探索乳腺癌生物学的研究人员组成,并通过更好的 了解这种生物学,以提高治愈率和治疗疾病。的长处 该中心将补充、加强和扩大NSABP的目标。在过去的五年里,我们 在贝勒医学院建立了临床存在和基础设施, 招募各种患者进行治疗研究。沿着我们的乳房护理中心, 与卫理公会医院合作成立,我们还成功地建立了一个 本·陶布总医院是一家县医院, 一些患有乳腺癌的弱势群体和少数民族妇女,并成功地从这一群体中招募 人口在过去的二十五年里,中心的研究人员在以下方面积累了相当多的专业知识: 预后和预测治疗反应的分子标志物,最近已经扩展到 他们在高通量基因组技术上的努力。通过一只忙碌的合力, 大量的临床服务和建立的临床试验基础设施,沿着科学家和临床医生深入 在翻译和分子标记研究方面经验丰富,我们将能够做出独特的贡献 实现NSABP为所有乳腺癌妇女提供最佳、个性化治疗的目标。
英文摘要
The Breast Care Center at Baylor College of Medicine is a broad based, multidiscipiinary organization composed of investigators dedicated to exploring the biology of breast cancer, and through a better understanding of this biology, to improving cure rates and treatments for the disease. The strengths of the Center will complement, reinforce, and extend the goals of the NSABP. Over the past five years, we have established a clinical presence and infrastructure at Baylor College of Medicine which facilitates the recruitment of a wide variety of patients onto treatment studies. Along with our Breast Care Center, established in collaboration with The Methodist Hospital, we have also been successful in establishing a dedicated breast oncology clinic at Ben Taub General Hospital, a county hospital which serves a large number of disadvantaged and minority women with breast cancer, and are successfully recruiting from this population. Center investigators have developed a considerable expertise over the past twenty-five years in molecular markers of prognosis and prediction of response to therapy, and most recently have extended their efforts into high through-put genomic technologies. Through the combined strength of a busy, high volume clinical service and established clinical trial infrastructure, along with scientists and clinicians deeply experienced in translational and molecular marker research, we will be able to make a unique contribution towards the NSABP's goal of optimum, individualized treatment for all women with breast cancer.
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Dual targeting of PI3K and NOS pathways in Metaplastic BreastCancer (MBC)
A phase II multi-center trial evaluating dual targeting of the PI3K/AKT and NOS pathways for treating metaplastic breast cancer (MpBC)
A phase II multi-center trial evaluating dual targeting of the PI3K/AKT and NOS pathways for treating metaplastic breast cancer (MpBC)
Targeting the Inflammasome As a Treatment Strategy for COVID-19 infected cancer patients
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