经济组统计办公室-猫眼课题宝

经济组统计办公室

批准号：

7276141

负责人：

ROBERT J GRAY

金额：

$236.71万

依托单位：

DANA-FARBER CANCER INST

依托单位国家：

美国

项目类别：

财政年份：

1978

资助国家：

美国

项目状态：

已结题

起止时间：

1978-03-01 至 2010-04-30

来源：

https://reporter.nih.gov/project-details/7276141

关键词：

AML/MDS Access to Information Accounting Activation Date Acute Acute Promyelocytic Leukemia Address Adjuvant Adjuvant Study Administrator Adopted Adoption Adult Adverse Drug Experience Reporting System Adverse effects Adverse event Affect African American Agreement Algorithms All Sites Amendment American College of Radiology American Society of Clinical Oncology American Society of Hematology Antigens Application procedure Area Authorization documentation Award Back Basic Science Bayesian Analysis Bibliography Bioinformatics Biological Markers Biometry Bite Blinded Blood Books Brain Brain Neoplasms Breast Budgets Business Rules Businesses CD-ROM Cancer Center Cancer Control Cancer Patient Cancer Survivor Cancer Therapy Evaluation Program Cancer Trials Support Unit Cancer and Leukemia Group B Carboxyamidotriazole Case Report Form Case Study Categories Caucasians Caucasoid Race Charge Chemistry Chest Cisplatin Class Classification Clinic Clinical Clinical Data Clinical Data Update System Clinical Investigator Clinical Protocols Clinical Research Clinical Research Associate Clinical Trials Clinical Trials Cooperative Group Clinical Trials Data Monitoring Committees Clinical Trials Design Clinics and Hospitals Closure Code Coin Collection Colon Carcinoma Commit Committee Members Common Data Element Common Terminology Criteria for Adverse Events Communication Communities Community Clinical Oncology Program Complex Complication Computer Security Computer Systems Computer Systems Development Computer software Computers Concept Review Conduct Clinical Trials Confidence Intervals Confidentiality Conflict of Interest Congresses Consent Consent Forms Contractor Contracts Controlled Clinical Trials Controlled Study Copyright Correlative Study Count Critiques Cross-Over Studies Custom Cytotoxic agent Daily Dana-Farber Cancer Institute Data Data Analyses Data Base Management Data Collection Data Coordinating Center Data Element Data Files Data Quality Data Reporting Data Set Data Storage and Retrieval Database Management Systems Databases Date of birth Date/Time Decision Making Derivation procedure Development Development Plans Devices Diabetes Mellitus Diagnostic Imaging Dictionary Digit structure Discipline Disease Disorder by Site Doctor of Philosophy Documentation Dose Dose-Limiting Drug Formulations Eastern Cooperative Oncology Group Education Educational Status Educational workshop Effectiveness Elderly Electronic Mail Electronics Elements Eligibility Determination Employee End Point Enrollment Ensure Environment Equilibrium Equipment and supply inventories Ethnic Origin Ethnic group Evaluation Evaluation Studies Event Exercise stress test Expectancy Experimental Designs Extensible Markup Language Factor Analysis Faculty Failure FarGo Feasibility Studies Feedback Floor Focus Groups Follow-Up Studies Foundations Freezing Funding Future GDF15 gene Gender Generations Genus - Lotus Goals Grant Gray unit of radiation dose Group Meetings Group Processes Group Purchasing Guidelines Hand Head Head and Neck Cancer Head and neck structure Health Insurance Portability and Accountability Act Health behavior Healthcare Hematology Hodgkin Disease Hormonal Hospital Records Hospitals Hour Housing Human Human Resources Human Subject Research Image Impact evaluation Incidence Individual Industry Information Services Information Systems Information Technology Informed Consent Institutes Institution Intention Intercept Interferon-alpha International Internet Intervention Investigation Journals Label Laboratories Laboratory Scientists Laboratory Study Language Latex Lead Leadership Learning Left Letters Librarians Libraries Licensing Life Lilium Link Literature Local Area Networks Location Logic Lymphoma Mails Maintenance Malignant Neoplasms Malignant neoplasm of gastrointestinal tract Malignant neoplasm of kidney Malignant neoplasm of lung Management Information Systems Manuals Manuscripts Maps Marketing Massachusetts Measurement Measures Mediation Medical Records Melissa Mentors Metastatic Melanoma Methodology Methods Minority Mission Modality Modeling Modification Monitor Motivation Multi-Institutional Clinical Trial Multiple Myeloma Names National Cancer Institute Natural regeneration Nature New Agents Nodal Non-Small-Cell Lung Carcinoma Nonprofit Organizations Normal Range North Central Cancer Treatment Group Notification Numbers Nurses Object Attachment Office of Administrative Management Oncologic Nursing Oncology Nurse One-Step dentin bonding system Online Systems Operative Surgical Procedures Outcome Output PLAB Protein Paper Parents Participant Pathologist Pathology Pathology Report Patient Noncompliance Patient Selection Patients Pattern Peer Review Performance Pharmaceutical Preparations Pharmacologic Substance Phase Phase I Clinical Trials Phase II Clinical Trials Phase III Clinical Trials Physicians Pilot Projects Planet Mars Plant Roots Play Pliability Plug-in Policies Policy Developments Population Positioning Attribute Pre-study Preparation Prevention Price Principal Investigator Printing Privacy Probability Procedures Process Production Prognostic Factor Progress Reports Progression-Free Survivals Prohibit Protocol Compliance Protocols documentation Public Health Schools Publications Published Comment Publishing Purpose Quality Control Quality of life Race Radiation Oncology Radiation Therapy Oncology Group Radiation therapy Randomized Randomized Controlled Clinical Trials Range Rate Reaction Reading Recommendation Recording of previous events Records Recurrence Relative (related person)Reliance Renal Cell Carcinoma Renal carcinoma Reporting Request for Applications Research Research Design Research Ethics Committees Research Infrastructure Research Personnel Reservations Resolution Resources Retrieval Risk Risk Factors Role Route Running Ruta SAS Safety Sample Size Sampling Scanning Schedule Science Scientist Score Screening procedure Second Primary Cancers Secure Security Series Serious Adverse Event Services Side Significance Level Site Site Visit Social Security Number Software Validation Solid Solid Neoplasm Solutions Source Southwest Oncology Group Specialist Specific qualifier value Specimen Speed Spottings Stable Disease Staff Development Staging Standard Preparations Standardization Standards of Weights and Measures Statistical Computing Statistical Methods Statistical Study Stratification Stratification Factors Structure Study Section Subgroup Supervision Support System Survival Rate Suspension substance Suspensions System Target Populations Technical Expertise Technology Telefacsimile Telephone Terminology Testing Text Therapeutic Therapeutic Clinical Trial Therapeutic Studies Thesauri Thinking Thoracic Oncology Tigers Time Time Study Tissue Banks Tissue Sample Tissues Title To specify Toxic effect Toxicity due to chemotherapy Training Training Activity Training Programs Training and Education Translating Transplantation Travel Treatment Protocols Treatment Step Tretinoin Uncontrolled Study United States Food and Drug Administration Universities Update Upper arm Urogenital Cancer Valid Value Validation Vendor Virus Visit Voting Waiting Lists Walking Week Weight Woman Work Workload Writing abstracting adjudicate administrative database anticancer research base cancer therapy chemotherapy clinical application commercial application computer generated computerized computerized data processing concept cost cost effective dalton data integrity data management database design day demographics design development policy digital disorder prevention efficacy evaluation encryption expectation experience falls file format firewall follow-up frontier hazard human subject improved indexing innovation instrument interest lecturer lectures leukemia leukemia/lymphoma malignant breast neoplasm medical schools melanoma member microwave electromagnetic radiation migration new technology optical character recognition outcome forecast patient safety payment pressure prevent probation prognostic programs protocol development quality assurance racial and ethnic response sarcoma simulation size skills software development software systems statistical center statistics success symposium symptom management syntax technical report theories time use tool tool development trafficking transmission process treatment duration treatment effect treatment trial tumor upper GI series validation studies web based interface web interface

项目摘要

项目成果

ROBERT J GRAY的其他基金

相似基金

相关文献

中文摘要

翻译

描述（由申请人提供）：本申请要求为ECOG统计中心提供六年的支持。这是统计局和数据管理局分别获奖的合并说明。统计中心的目标是在临床和实验室研究的设计和分析、数据库分析和研究者发起的赠款、研究监查、数据管理程序和系统、数据处理和质量控制、教育和培训活动、行政管理和信息系统等领域为ECOG提供领导和支持。在此期间，ECOG统计学家继续保持其在临床试验设计和分析方面的强大领导传统。这些统计学家是143篇已发表的ECOG论文的合著者，进行了大量的数据库分析，现在每年为大约10个由卫生部发起的赠款提供支持。在过去5年中，数据管理方面的一些主要成就包括：改变数据管理程序，以提高效率和标准化，包括增加使用计算机处理，改进程序文件，改变组间研究数据的路由，积极参与NCI的通用数据元素项目，以标准化数据术语，开发标准化程序和计算机应用程序，用于处理新实体瘤缓解标准的数据，建立和实施ECOG研究随访持续时间指南，并终止许多旧研究的随访，并制定政策，以促进ECOG成员机构遵守HIPAA隐私规则。在旧的Ingres数据库环境中开发更好的计算机应用程序进行数据管理的努力最终使人们认识到，这不是一个为未来发展所依赖的适当平台。在对各种选项进行调查后，ECOG决定将其数据管理操作转换为Oracle Clinical。转换工作取得了重大进展，第一项研究于5月初在甲骨文公司投入生产。30多年来，数据来自数百项研究，数百个应用程序和报告访问存储在Ingres中的ECOG数据库和管理表，数据迁移和应用程序转换的过程将持续数年。这将是下一个赠款期早期数据管理和信息系统（IS）组的主要开发活动。 IS小组在上一个资助期内开发了许多重要的新应用程序，包括增强ECOG网站、用于处理加速不良事件系统的新工具、新的随访预期报告工具、用于血液学/化学相关毒性自动分级的数据库程序、用于处理应答数据的工具、增强对财务管理和报销的支持以及新的监管支持系统。SAS程序员开发了一套宏指令，以支持数据检索、报告和分析，并执行各种数据质量控制检查。未来的信息系统计划包括实施改进的文件管理系统、安全通信系统和文件成像系统，以便在线提供表格和其他文件。

英文摘要

DESCRIPTION (provided by applicant): This application requests six years of support for the ECOG Statistical Center. It is a combined narrative for the separate awards for the Statistical Office and the Data Management Office. The objectives of the Statistical Center are to provide leadership and support for ECOG in the areas of design and analysis of clinical and laboratory studies, database analyses and investigator initiated grants, study monitoring, data management procedures and systems, processing and quality control of data, education and training activities, administrative management, and information systems. During this period, ECOG statisticians have continued their strong tradition of leadership in the design and analysis of clinical trials. The statisticians have been coauthors on 143 published ECOG papers, have performed numerous database analyses, and are now providing support for approximately 10 investigator-initiated grants per year. Some of the major accomplishments in data management during the last 5 years include changes in data management procedures to improve efficiency and standardization, including increasing use of computerized processing, improved documentation of procedures, and changes in the routing of data on intergroup studies, active participation in the NCI's Common Data Elements project to standardize data terminology, development of standardized procedures and computer applications for processing data for the new solid tumor response criteria, establishing and implementing guidelines for follow-up durations on ECOG studies and terminating follow-up on many old studies, and development of policies to facilitate compliance with the HIPAA privacy rule by ECOG's member institutions. The efforts to develop better computer applications for data management within the old Ingres database environment eventually led to the realization that it was not an adequate platform on which to build for the future. After investigation of various options, ECOG decided to convert its data management operation to Oracle Clinical. Significant progress on the conversion has been made, with the first study going into production in Oracle in early May. With over 30 years of data from hundreds of studies, and hundreds of applications and reports that access the ECOG database and administrative tables stored in Ingres, the process of data migration and application conversion will continue for several years. This will be the dominant development activity in both data management and in the Information Systems (IS) group for the early part of the next grant period. The IS group has developed a number of important new applications during the last grant period, including enhancements to the ECOG web site, new tools for processing expedited adverse event systems, new follow-up expectancy reporting tools, database procedures for automatic grading of hematology/chemistry related toxicities, tools for processing response data, enhanced support for fiscal management and reimbursement, and new regulatory support systems. The SAS programmers have developed a suite of macros to support data retrieval, reporting and analysis and for performing a variety of data quality control checks. Future Information Systems plans include implementation of improved document management systems, secure communications systems, and document imaging systems for on-line availability of forms and other documents.

期刊论文(0)

专著(0)

科研奖励(0)

会议论文