Transferring Integrase Technology to Animals

将 Integrase 技术转移到动物身上

• 批准号: 7482694
• 负责人: MICHELE P CALOS
• 金额: $ 35.61万
• 依托单位: STANFORD UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-07-01 至 2008-08-19
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7482694
• 关键词: A Mouse; Acceleration; Achievement; Address; Animals; Bacteriophages; Biological Assay; Canis familiaris; Catheters; Cells; Clinic; Clinical; Clinical Trials; DNA; Development; Disease; Disease model; Dose; Factor VIII; Family suidae; Gene Expression; Gene Transduction Agent; Genetic Screening; Genome; Genomics; Goals; Grant; Hemophilia A; Human; Human Chromosomes; Human Genome; Incidence; Injection of therapeutic agent; Insertional Mutagenesis; Integrase; Knockout Mice; Left lobe of liver; Liver; Liver diseases; Liver neoplasms; Location; Longevity; MYC gene; Macaca mulatta; Malignant Neoplasms; Malignant neoplasm of liver; Mammalian Cell; Mammals; Mediating; Methods; Monkeys; Movement; Mus; Muscle; Patients; Plasmids; Polymerase Chain Reaction; Range; Reaction; Risk; Rodent Model; Safety; Site; Specificity; Streptomyces phage phiC31; Sus scrofa; System; Tail; Technology; Testing; Therapeutic; Time; Tissues; Transgenic Animals; Translating; Veins; Viral; Work; Xq22.1; base; clinical application; gene therapy; immunogenicity; improved; in vivo; innovation; liver biopsy; mouse model; mutant; new technology; nonhuman primate; pressure; research study; site-specific integration; therapeutic gene; transgene expression; tumor; vector