Developing A Collaborative Care Strategy for Depression and Co-Morbid CHF
制定针对抑郁症和共病 CHF 的协作护理策略
基本信息
- 批准号:7253852
- 负责人:
- 金额:$ 18.35万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2007
- 资助国家:美国
- 起止时间:2007-05-10 至 2010-04-30
- 项目状态:已结题
- 来源:
- 关键词:Academic Medical CentersAcuteAddressAdherenceAdoptedAffectAmericanAnxiety DisordersAreaAttentionCardiacCardiovascular DiseasesCardiovascular systemCare given by nursesCaringCase ManagerCessation of lifeChronic DiseaseClassClinicalClinical DataClinical ResearchClinical TrialsCohort StudiesConditionCongestiveCongestive Heart FailureCoronary Artery BypassDataDepressed moodDevelopmentDiagnosisDisease ManagementEffectivenessEnrollmentEvidence based treatmentFacilities and Administrative CostsFailureFundingGenderGuidelinesHealthHealth Care CostsHealth Planning OrganizationsHealthcareHeartHeart failureHospitalizationHospitalsIndividualInpatientsInterventionLeftManaged CareManualsMedicalMedical centerMental DepressionMorbidity - disease rateNational Institute of Mental HealthNew YorkNewly DiagnosedNumbersNursesOperative Surgical ProceduresOutcomeOutpatientsPatient Self-ReportPatientsPatternPhasePhysiciansPrimary Health CareProcess MeasureProtocols documentationProviderPsyche structureQuality of CareRaceRangeRateReportingResearch PersonnelResolutionResourcesRiskScoreScreening procedureServicesSeveritiesSeverity of illnessSupervisionTelephoneTestingTrainingTreatment ProtocolsUniversitiesUpdateVentricularWorkbaseclinically significantcohortcollaborative carecompare effectivenessdepressive symptomseffectiveness trialexperiencefollow-uphealth care service utilizationhealth related quality of lifehospital readmissionimprovedinterestmortalitynovelprogramsresponsetherapy development
项目摘要
DESCRIPTION (provided by applicant): Congestive heart failure (CHF) is a common and growing health problem that affects 5 million Americans, with over 550,000 newly diagnosed cases, 287,000 deaths, and $30 billion in direct and indirect costs yearly. Despite a number of care management programs that are being adopted by private and public payers, CHF patients continue to experience poor outcomes. A potential contributor to these poor outcomes is the presence of depression, present in approximately 20-50% of CHF patients.
Similar principles of effective chronic disease management apply to both depression and to CHF. Thus, we suggest that screening CHF patients for depression and then utilizing a single nurse care manager working under a physician's supervision to simultaneously deliver evidence-based treatments for both conditions when present is a novel and potentially more sustainable strategy for improving clinical outcomes than referring depressed CHF patients to separate care providers.
Our revised three-year R34 treatment development proposal is responsive to NIMH PAR-06-248, From Intervention Development to Services, as its specific aims are to obtain the necessary feasibility and clinical data required to plan a large-scale R01 trial which will compare the effectiveness of a "blended" depression/CHF care management program with current CHF care management programs in reducing depressive symptoms, improving HRQoL, and various other outcomes of interest. It consists of four coordinated phases: (1) Training; (2) Manual Development; (3) Cohort Study; and (4) Pilot Intervention. We will send nurse-recruiter/care managers from our present NIH-funded trial to treat post-CABG depression for training in two local in-patient and out-patient CHF care management programs. We subsequently will integrate the stepped collaborative care protocols for treating depression we developed in our earlier work with guideline-based protocols for treating CHF. Next, we will conduct a cohort study to estimate recruitment and "usual care" treatment patterns for 372 depressed and 100 non-depressed CHF patients. ROC analyses will be applied so as to estimate suitably sensitive and specific PHQ-9 cut-off scores for identifying depressed patients who are likely to die or become rehospitalized at 6-month follow-up. Finally, we will pilot our telephone-based "blended" collaborative care strategy to 30 depressed CHF patients to further refine our treatment strategy.
充血性心力衰竭(CHF)是一种常见且日益严重的健康问题,影响着500万美国人,每年有超过550,000例新诊断病例,287,000例死亡,直接和间接费用为300亿美元。尽管私人和公共支付者正在采用一些护理管理计划,但CHF患者的结局仍然很差。这些不良结局的潜在因素是抑郁症的存在,约20-50%的CHF患者存在抑郁症。
类似的有效慢性病管理原则适用于抑郁症和CHF。因此,我们建议,筛选CHF患者的抑郁症,然后利用一个单一的护士护理经理在医生的监督下工作,同时提供基于证据的治疗,这两种情况时,是一种新的和潜在的更可持续的战略,以改善临床结果比抑郁CHF患者单独的护理提供者。
我们修订的三年R34治疗开发提案响应NIMH PAR-06-248,从干预开发到服务,因为其具体目标是获得计划大规模R 01试验所需的必要可行性和临床数据,该试验将比较“混合”抑郁/CHF护理管理计划与当前CHF护理管理计划在减少抑郁症状方面的有效性,改善HRQoL和各种其他感兴趣的结果。它包括四个协调阶段:(1)培训;(2)手册开发;(3)队列研究;(4)试点干预。我们将从我们目前NIH资助的试验中派遣护士招募人员/护理经理,以治疗CABG后抑郁症,并在两个当地住院和门诊CHF护理管理项目中进行培训。随后,我们将整合我们在早期工作中开发的用于治疗抑郁症的阶梯式协作护理协议与用于治疗CHF的基于指南的协议。接下来,我们将进行一项队列研究,以估计372例抑郁和100例非抑郁CHF患者的招募和“常规护理”治疗模式。将应用ROC分析,以估计适当敏感和特异性的PHQ-9截止评分,用于识别在6个月随访时可能死亡或再次住院的抑郁患者。最后,我们将对30名抑郁性CHF患者试行基于电话的“混合”协作护理策略,以进一步完善我们的治疗策略。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
数据更新时间:{{ journalArticles.updateTime }}
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
数据更新时间:{{ journalArticles.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ monograph.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ sciAawards.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ conferencePapers.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ patent.updateTime }}
BRUCE Lawrence ROLLMAN其他文献
BRUCE Lawrence ROLLMAN的其他文献
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
{{ truncateString('BRUCE Lawrence ROLLMAN', 18)}}的其他基金
Blended Collaborative Care for Heart Failure and Co-Morbid Depression
心力衰竭和共病抑郁症的混合协作护理
- 批准号:
8437510 - 财政年份:2013
- 资助金额:
$ 18.35万 - 项目类别:
Blended Collaborative Care for Heart Failure and Co-Morbid Depression
心力衰竭和共病抑郁症的混合协作护理
- 批准号:
8710331 - 财政年份:2013
- 资助金额:
$ 18.35万 - 项目类别:
Online Treatments for Mood and Anxiety Disorders in Primary Care
初级保健中情绪和焦虑症的在线治疗
- 批准号:
8235150 - 财政年份:2012
- 资助金额:
$ 18.35万 - 项目类别:
Online Treatments for Mood and Anxiety Disorders in Primary Care
初级保健中情绪和焦虑症的在线治疗
- 批准号:
8598831 - 财政年份:2012
- 资助金额:
$ 18.35万 - 项目类别:
Online Treatments for Mood and Anxiety Disorders in Primary Care
初级保健中情绪和焦虑症的在线治疗
- 批准号:
8423688 - 财政年份:2012
- 资助金额:
$ 18.35万 - 项目类别:
Developing A Collaborative Care Strategy for Depression and Co-Morbid CHF
制定针对抑郁症和共病 CHF 的协作护理策略
- 批准号:
7418923 - 财政年份:2007
- 资助金额:
$ 18.35万 - 项目类别:
Developing A Collaborative Care Strategy for Depression and Co-Morbid CHF
制定针对抑郁症和共病 CHF 的协作护理策略
- 批准号:
7615731 - 财政年份:2007
- 资助金额:
$ 18.35万 - 项目类别:
相似海外基金
Acute senescence: a novel host defence counteracting typhoidal Salmonella
急性衰老:对抗伤寒沙门氏菌的新型宿主防御
- 批准号:
MR/X02329X/1 - 财政年份:2024
- 资助金额:
$ 18.35万 - 项目类别:
Fellowship
Transcriptional assessment of haematopoietic differentiation to risk-stratify acute lymphoblastic leukaemia
造血分化的转录评估对急性淋巴细胞白血病的风险分层
- 批准号:
MR/Y009568/1 - 财政年份:2024
- 资助金额:
$ 18.35万 - 项目类别:
Fellowship
Combining two unique AI platforms for the discovery of novel genetic therapeutic targets & preclinical validation of synthetic biomolecules to treat Acute myeloid leukaemia (AML).
结合两个独特的人工智能平台来发现新的基因治疗靶点
- 批准号:
10090332 - 财政年份:2024
- 资助金额:
$ 18.35万 - 项目类别:
Collaborative R&D
Cellular Neuroinflammation in Acute Brain Injury
急性脑损伤中的细胞神经炎症
- 批准号:
MR/X021882/1 - 财政年份:2024
- 资助金额:
$ 18.35万 - 项目类别:
Research Grant
KAT2A PROTACs targetting the differentiation of blasts and leukemic stem cells for the treatment of Acute Myeloid Leukaemia
KAT2A PROTAC 靶向原始细胞和白血病干细胞的分化,用于治疗急性髓系白血病
- 批准号:
MR/X029557/1 - 财政年份:2024
- 资助金额:
$ 18.35万 - 项目类别:
Research Grant
Combining Mechanistic Modelling with Machine Learning for Diagnosis of Acute Respiratory Distress Syndrome
机械建模与机器学习相结合诊断急性呼吸窘迫综合征
- 批准号:
EP/Y003527/1 - 财政年份:2024
- 资助金额:
$ 18.35万 - 项目类别:
Research Grant
FITEAML: Functional Interrogation of Transposable Elements in Acute Myeloid Leukaemia
FITEAML:急性髓系白血病转座元件的功能研究
- 批准号:
EP/Y030338/1 - 财政年份:2024
- 资助金额:
$ 18.35万 - 项目类别:
Research Grant
STTR Phase I: Non-invasive focused ultrasound treatment to modulate the immune system for acute and chronic kidney rejection
STTR 第一期:非侵入性聚焦超声治疗调节免疫系统以治疗急性和慢性肾排斥
- 批准号:
2312694 - 财政年份:2024
- 资助金额:
$ 18.35万 - 项目类别:
Standard Grant
ロボット支援肝切除術は真に低侵襲なのか?acute phaseに着目して
机器人辅助肝切除术真的是微创吗?
- 批准号:
24K19395 - 财政年份:2024
- 资助金额:
$ 18.35万 - 项目类别:
Grant-in-Aid for Early-Career Scientists
Collaborative Research: Changes and Impact of Right Ventricle Viscoelasticity Under Acute Stress and Chronic Pulmonary Hypertension
合作研究:急性应激和慢性肺动脉高压下右心室粘弹性的变化和影响
- 批准号:
2244994 - 财政年份:2023
- 资助金额:
$ 18.35万 - 项目类别:
Standard Grant