NIH 院长先锋奖-猫眼课题宝

NIH 院长先锋奖

批准号：

7269949

负责人：

JUNYING YUAN

金额：

$82.76万

依托单位：

HARVARD MEDICAL SCHOOL

依托单位国家：

美国

项目类别：

财政年份：

2005

资助国家：

美国

项目状态：

已结题

起止时间：

2005-09-30 至 2010-07-31

来源：

https://reporter.nih.gov/project-details/7269949

关键词：

14q12 Address Adult Affect Alzheimer&apos s Disease American Amyloid Fibrils Amyloid beta-Protein Animals Antithrombins Apoptosis Autophagocytosis Award BH3 Domain Behavior Binding Biochemistry Biological Models Biology Biomedical Research Birds Caenorhabditis elegans Calculi Cardiovascular system Caspase Caspase-1 Cell Death Cell physiology Cells Cellular biology Cessation of life Chemicals Chemistry China Chromosomes Cirrhosis Class Collaborations Complex Condition Congo Red Culture Media Cultured Cells Death Domain Defect Dementia Developmental Biology Discipline of Nursing Disease Disruption Disulfide Linkage Doctor of Philosophy Dominant-Negative Mutation Dyes Education Endopeptidases Endoplasmic Reticulum Environment Enzymes Event Fellowship Fibroblasts Floor Foundations Friends Functional disorder Future General Hospitals Genes Genets Genome Green Fluorescent Proteins Health Heart Homologous Gene Human Human Genome Huntington Disease Ice Immune system In Vitro Inclusion Bodies Individual Induction of Apoptosis Institutes Institution Interleukin-1 Intuition Ischemic Brain Injury Journals Knowledge Labyrinth Lead Libraries Link Liver Location Lysosomes Maps Massachusetts Mediating Medical Surveillance Medicine Mentors Microinjections Mining Mitochondria Modeling Molecular Molecular Chaperones Molecular Conformation Motor Mus Mutation Names Nature Necrosis Nematoda Nerve Degeneration Neuraxis Neurodegenerative Disorders Neurons Neurosciences Numbers Occupations Organ Organelles Paper Parkinson Disease Pathology Pathway interactions Patients Peer Review Peptide Hydrolases Phosphoric Monoester Hydrolases Phosphorylation Point Mutation Population Positioning Attribute PrPSc Proteins Prevention Prion Diseases Prions Process Professional Education Property Protein C Inhibitor Protein Conformation Protein Dephosphorylation Protein Family Protein Synthesis Inhibition Proteins Publishing Range Recruitment Activity Regulation Research Research Personnel Research Support Resistance Rest Risk Role Science Sensorineural Hearing Loss Stress Stroke Structure Students Study Section Symptoms Technology Testing Therapeutic Thrombosis Time Title Transgenic Mice Trustees Uncertainty United States National Institutes of Health Universities University of Texas M D Anderson Cancer Center Up-Regulation Walking Wild Type Mouse Withdrawal Work age related base biological adaptation to stress caspase 12 caspase-2 caspase-8 cell suicide concept coping cytotoxicity day desire dimer editorial factor C gain of function hearing impairment high throughput screening human Huntingtin protein human disease in vivo inhibitor/antagonist insight intermolecular interaction medical schools multicatalytic endopeptidase complex mutant neuron loss neuronal survival novel polyglutamine polymerization post-doctoral training pressure prevent professor programs protein aggregation protein degradation protein expression protein folding protein function protein misfolding protein oligomer repaired response small molecule small molecule libraries success tool trend unpublished works

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会议论文

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批准号：

9066393
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资助金额：

$7.77万
财政年份：

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JUNYING YUAN
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HARVARD MEDICAL SCHOOL

Investigating the neuroinflammatory role of RIP1 kinase

批准号：

8670893
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$34.75万
财政年份：

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Investigating the neuroinflammatory role of RIP1 kinase

批准号：

8848334
项目类别：
资助金额：

$33.71万
财政年份：

2014
负责人：

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HARVARD MEDICAL SCHOOL

Investigating the mechanism of TNFalpha mediated cell death in oligodendrocytes

批准号：

8729514
项目类别：
资助金额：

$36.71万
财政年份：

2013
负责人：

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依托单位：

HARVARD MEDICAL SCHOOL

Investigating the mechanism of TNFalpha mediated cell death in oligodendrocytes

批准号：

8620945
项目类别：
资助金额：

$37.08万
财政年份：

2013
负责人：

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依托单位：

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Investigating the mechanism of TNFalpha mediated cell death in oligodendrocytes

批准号：

8851697
项目类别：
资助金额：

$37.08万
财政年份：

2013
负责人：

JUNYING YUAN
依托单位：

HARVARD MEDICAL SCHOOL

Investigating the mechanism of TNFalpha mediated cell death in oligodendrocytes

批准号：

9084667
项目类别：
资助金额：

$37.08万
财政年份：

2013
负责人：

JUNYING YUAN
依托单位：

HARVARD MEDICAL SCHOOL

Molecular mechanism of a cellular necrotic cell death pathway

批准号：

7633055
项目类别：
资助金额：

$35.0万
财政年份：

2009
负责人：

JUNYING YUAN
依托单位：

HARVARD MEDICAL SCHOOL

A High Throughput Screen for Inhibitors of a Novel Necrotic Cell Death Pathway

批准号：

7304402
项目类别：
资助金额：

$2.5万
财政年份：

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负责人：

JUNYING YUAN
依托单位：

HARVARD MEDICAL SCHOOL

Development of Anti-necrosis Drug for Acute Brain Injury

批准号：

7100711
项目类别：
资助金额：

$126.13万
财政年份：

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负责人：

JUNYING YUAN
依托单位：

HARVARD MEDICAL SCHOOL

AUTOPHAGY, DNA DAMAGE AND ONSET OF HUNTINGTON'S DISEASE.

批准号：

7085095
项目类别：
资助金额：

$33.83万
财政年份：

2006
负责人：

JUNYING YUAN
依托单位：

HARVARD MEDICAL SCHOOL

Development of Anti-necrosis Drug for Acute Brain Injury

批准号：

7495127
项目类别：
资助金额：

$25.7万
财政年份：

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负责人：

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依托单位：

HARVARD MEDICAL SCHOOL

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批准号：

7276709
项目类别：
资助金额：

$100.22万
财政年份：

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负责人：

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依托单位：

HARVARD MEDICAL SCHOOL

NIH Director's Pioneer Award

批准号：

7128519
项目类别：
资助金额：

$82.76万
财政年份：

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负责人：

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依托单位：

HARVARD MEDICAL SCHOOL

NIH Director's Pioneer Award

批准号：

7672469
项目类别：
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$82.76万
财政年份：

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负责人：

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依托单位：

HARVARD MEDICAL SCHOOL

NIH Director's Pioneer Award (RMI)

批准号：

7080994
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依托单位：

HARVARD MEDICAL SCHOOL

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批准号：

6835700
项目类别：
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$22.97万
财政年份：

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依托单位：

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Dissecting the Molecular Pathway of Aponecrosis

批准号：

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依托单位：

HARVARD MEDICAL SCHOOL

Dissecting the Molecular Pathway of Aponecrosis

批准号：

6422532
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依托单位：

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6683213
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海外基金