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NIH Director's Pioneer Award

NIH Director's Pioneer Award
NIH 院长先锋奖
批准号:
7672469
负责人:
JUNYING YUAN
金额:
$82.76万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2005
资助国家:
美国
项目状态:
已结题
起止时间:
2005-09-30 至 2012-07-31
关键词:
14q12AddressAdultAffectAllelesAlzheimer&aposs DiseaseAmericanAmino AcidsAmyloid FibrilsAmyloid beta-ProteinAnimalsAntithrombinsApoptosisAutophagocytosisAwardBH3 DomainBackBehaviorBindingBiochemistryBiological AssayBiological ModelsBiologyBiomedical ResearchBirdsBlast CellCaenorhabditis elegansCalculiCardiovascular systemCaspaseCaspase-1Cell Culture TechniquesCell DeathCell physiologyCellsCellular biologyCessation of lifeChemicalsChemistryChinaChromosomesCirrhosisCollaborationsComplexCongo RedCowpox virusCulture MediaCysteine ProteaseDeath DomainDefectDementiaDevelopmentDevelopmental BiologyDiscipline of NursingDiseaseDisulfide LinkageDoctor of PhilosophyDominant-Negative MutationDue ProcessDyesEducationEmbryonic DevelopmentEndoplasmic ReticulumEnvironmentEnzymesEventEvolutionFacultyFeelingFellowshipFibroblastsFloorFoundationsFriendsFunctional disorderFutureGeneral HospitalsGenesGeneticGenetsGenomeHandHealthHeartHomologous GeneHumanHuman GenomeHuntington DiseaseHusbandIceImageImmune systemIn VitroInclusion BodiesIndividualInduction of ApoptosisInstitutesInstitutionInterleukin ActivationInterleukin-11Interleukin-3InterleukinsIntuitionIschemic Brain InjuryJournalsKnowledgeLaboratoriesLabyrinthLeadLearningLeftLengthLibrariesLinkLiverLocationLysosomesMammalian CellMammalsMapsMassachusettsMediatingMedicineMentorsMethodsMicroinjectionsMindMiningMitochondriaModelingMolecularMolecular ChaperonesMolecular ConformationMotorMusMutationNamesNatureNecrosisNematodaNerve DegenerationNeuraxisNeurobiologyNeurodegenerative DisordersNeuronsNeurosciencesOccupationsOrganOrganellesPaperParkinson DiseasePathologyPathway interactionsPatientsPeer ReviewPeptide HydrolasesPhosphoric Monoester HydrolasesPhosphorylationPoint MutationPopulationPositioning AttributePostdoctoral FellowPrPSc ProteinsPreventionPrion DiseasesPrionsProcessProfessional EducationPropertyProtein C InhibitorProtein ConformationProtein DephosphorylationProtein FamilyProtein Synthesis InhibitionProteinsProto-OncogenesPublishingRecruitment ActivityRegulationResearchResearch PersonnelResearch SupportResistanceRestReverse Transcriptase Polymerase Chain ReactionRiskRoleScienceSensorineural Hearing LossStarvationStressStrokeStructureStudentsStudy SectionSymptomsSystemTechnologyTestingTherapeuticThinkingThrombosisTimeTrainingTransfectionTransgenic MiceTrustTrusteesUncertaintyUnited States National Institutes of HealthUniversitiesUniversity of Texas M D Anderson Cancer CenterUp-RegulationVisitWalkingWild Type MouseWithdrawalWorkage relatedbasebiological adaptation to stresscDNA Librarycareercaspase 12caspase-2caspase-8cell suicidecopingcytotoxicitydeprivationdevelopmental neurobiologydimereditorialendoplasmic reticulum stressfactor Cfascinategain of functiongraduate studenthearing impairmenthigh throughput screeninghuman Huntingtin proteinhuman diseasein vivoinhibitor/antagonistinsightinterestintermolecular interactionmedical schoolsmeetingsmulticatalytic endopeptidase complexmutantnervous system disorderneuron developmentneuron lossneuronal survivalnovelpolyglutaminepolymerizationpost-doctoral trainingpressurepreventprion hypothesisprion-likeprofessorprogramsprotein aggregationprotein degradationprotein expressionprotein foldingprotein functionprotein misfoldingprotein oligomerrepairedresearch studyresponsesmall moleculesmall molecule librariessuccesstissue/cell culturetooltreatment strategytrendunpublished works

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中文摘要
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英文摘要
No Abstract provided
期刊论文(2)
专著(0)
科研奖励(0)
会议论文
DOI: 10.1016/j.immuni.2013.01.015
发表时间: 2013-05-23
期刊: IMMUNITY
影响因子: 32.4
作者: [Py, Benedicte F., Gonzalez, Santiago F., Long, Kai, Kim, Mi-Sung, Kim, Young-A., Zhu, Hong, Yao, Jianhua, Degauque, Nicolas, Villet, Regis, Ymele-Leki, Patrick, Gadjeva, Mihaela, Pier, Gerald B., Carroll, Michael C., Yuan, Junying]
通讯作者: Yuan, Junying
Investigating the neuroinflammatory role of RIP1 kinase
  • 批准号:
    9066393
  • 项目类别:
  • 资助金额:
    $7.77万
  • 财政年份:
    2014
  • 负责人:
    JUNYING YUAN
  • 依托单位:
Investigating the neuroinflammatory role of RIP1 kinase
  • 批准号:
    8670893
  • 项目类别:
  • 资助金额:
    $34.75万
  • 财政年份:
    2014
  • 负责人:
    JUNYING YUAN
  • 依托单位:
Investigating the neuroinflammatory role of RIP1 kinase
  • 批准号:
    8848334
  • 项目类别:
  • 资助金额:
    $33.71万
  • 财政年份:
    2014
  • 负责人:
    JUNYING YUAN
  • 依托单位:
Investigating the mechanism of TNFalpha mediated cell death in oligodendrocytes
  • 批准号:
    8729514
  • 项目类别:
  • 资助金额:
    $36.71万
  • 财政年份:
    2013
  • 负责人:
    JUNYING YUAN
  • 依托单位:
海外基金