Glycosyltransferase effectors of enteropathogenic E. coli and Salmonella

肠病性大肠杆菌和沙门氏菌的糖基转移酶效应子

• 批准号: nhmrc : GNT1090108
• 负责人: Dr Jaclyn Pearson
• 金额: $ 30.94万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Early Career Fellowships
• 财政年份: 2015
• 资助国家: 澳大利亚
• 起止时间: 2015-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/glycosyltransferase-effectors-enteropathogenic-coli-salmonella/1345782
• 关键词: Glycosyltransferase; effectors; enteropathogenic; E.; coli

This project aims to characterise the mechanisms of disease caused by bacterial pathogens including Salmonella and enteropathogenic E. coli. These pathogens cause a significant amount of diarrhoeal disease and mortality worldwide particularly in infants and in countries where water sanitation is poor. I aim to investigate the specific mechanisms the bacteria employ to manipulate and avoid our immune response during infection in order to better understand and combat diarrhoeal disease.

本项目旨在阐明沙门氏菌和肠致病性大肠杆菌等细菌病原体引起疾病的机制。杆菌这些病原体在世界范围内引起大量的腹泻和死亡，特别是在婴儿和水卫生条件差的国家。我的目标是研究细菌在感染过程中操纵和避免我们的免疫反应的具体机制，以便更好地了解和对抗肠道疾病。