Role of CD4+ and DN CD1d-Restricted T Cells in Type 1 Diabetes

CD4 和 DN CD1d 限制性 T 细胞在 1 型糖尿病中的作用

• 批准号: 7524017
• 负责人: S. Brian BRIAN Wilson
• 金额: $ 35.44万
• 依托单位: BRIGHAM AND WOMEN'S HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-04-01 至 2008-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7524017
• 关键词: Antigen-Presenting Cells; Antigens; Asses; Autoantigens; Autoimmune Diabetes; Autoimmune Process; Autoimmunity; Autologous; Binding; Cell Line; Cell physiology; Cells; Chimeric Proteins; Clinical; Defect; Dendritic Cells; Dendritic cell activation; Development; Diabetes Mellitus; Disease; Disease Progression; Disease susceptibility; Equilibrium; Functional disorder; Human; Human Volunteers; Immunologics; Inbred BB Rats; Inbred NOD Mice; Individual; Inflammatory; Inflammatory Response; Insulin-Dependent Diabetes Mellitus; Interleukin-10; Interleukin-4; Lipids; Modeling; Monoclonal Antibodies; Movement; Mus; Myelogenous; Nature; Pathogenesis; Patients; Peripheral Blood Mononuclear Cell; Play; Population; Process; Production; Proteins; Reporting; Risk; Rodent; Role; Sampling; Specificity; Staining method; Stains; Susceptibility Gene; T-Cell Proliferation; T-Lymphocyte; T-Lymphocyte Subsets; Testing; To autoantigen; Work; autoreactive T cell; autoreactivity; base; cell type; cytokine; cytotoxic; disease natural history; human subject; in vivo; perforin; prevent; response