Perceptions Of Benefits And Risks-Rakai

对收益和风险的看法-Rakai

• 批准号: 7215859
• 负责人: ezekiel J emanuel
• 金额: --
• 依托单位: CLINICAL CENTER
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/7215859
• 关键词: Africa; HIV infections; behavior therapy; behavioral /social science research tag; clinical research; community; epidemiology; ethics; focus groups; health science research analysis /evaluation; human population study; human subject; human therapy evaluation; international cooperation; interview; medically underserved population; perception; population survey; rural area; sexually transmitted diseases

This study seeks to collect empirical data to inform deliberation and resolution of ethical issues related to biomedical research in developing countries. In particular, this study will look at how research participants, community members, and opinion leaders in the Rakai District in Uganda perceive the benefits and risks to communities involved in biomedical research. The study will assess perceptions of the effect of research on individuals and communities. The Rakai Project is an ongoing prospective cohort study in the Rakai District of southwestern Uganda. It has an intensive population-based HIV/STD epidemiological, behavioral, and intervention research program in 46 communities in the district. A representative sample of men and women was drawn from communities in the Rakai District to include: 1) people who have participated in Rakai Project research (including both those who have received financial compensation for their participation and those who have not), 2) people who have never been asked to participate in research, 3) people who have declined to participate in research, and 4) people who are perceived as leaders by their communities. Men and women are interviewed come from deep rural, rural, and peri-urban communities. A quantitative survey has been administered to approximately 900 individuals; qualitative in-depth individual interviews and focus group discussions were also conducted. Data is being analyzed and manuscripts are in progress

本研究旨在收集经验数据，为发展中国家审议和解决与生物医学研究有关的伦理问题提供信息。特别是，本研究将研究乌干达Rakai区的研究参与者、社区成员和意见领袖如何看待参与生物医学研究的社区的利益和风险。这项研究将评估人们对研究对个人和社区的影响的看法。Rakai项目是一项正在乌干达西南部Rakai地区进行的前瞻性队列研究。它在该地区的46个社区开展了以人口为基础的艾滋病毒/性病流行病学、行为和干预研究计划。从Rakai地区的社区抽取了一个具有代表性的男性和女性样本，包括：1)参与Rakai项目研究的人（包括那些因参与而获得经济补偿和没有获得经济补偿的人），2)从未被要求参与研究的人，3)拒绝参与研究的人，以及4)被社区视为领导者的人。受访的男性和女性来自偏远的农村、农村和城郊社区。对大约900人进行了定量调查；定性深入的个人访谈和焦点小组讨论也进行了。目前正在分析数据，撰写手稿