DIABETES PREVENTION PROGRAM - OUTCOMES STUDY (DPP-OS)

糖尿病预防计划 - 结果研究 (DPP-OS)

• 批准号: 7603316
• 负责人: Neil H. White
• 金额: $ 3.32万
• 依托单位: WASHINGTON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-04-01 至 2007-09-16
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7603316
• 关键词: Cardiovascular Diseases; Computer Retrieval of Information on Scientific Projects Database; Effectiveness of Interventions; Funding; Grant; Health; Institution; Life Style; Metformin; Modification; Non-Insulin-Dependent Diabetes Mellitus; Outcome; Outcome Study; Research; Research Personnel; Resources; Risk Factors; Source; Testing; United States National Institutes of Health; base; diabetes prevention program; lifestyle intervention; prevent

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Subject who participated in the Diabetes Prevention Program (DPP) will be followed to assess their long-term outcomes. All subjects were offered a modified lifestyle intervention based on that offered during the DPP. We wish to continue to test the hypothesis that progression from IGT to type 2 diabetes can be prevented or delayed by intensive lifestyle modification or metformin and to evaluate the effects of these interventions on selected inividual health outcomes, including cardiovascular disease adn risk factors.

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 将对参加糖尿病预防计划（DPP）的受试者进行随访，以评估其长期结局。 所有受试者均接受了基于DPP期间提供的改良生活方式干预。 我们希望继续验证这一假设，即强化生活方式改变或二甲双胍可以预防或延迟IGT向2型糖尿病的进展，并评估这些干预措施对选定的个体健康结局（包括心血管疾病和危险因素）的影响。