TREATMENTS FOR WHIPLASH - ASSOCIATED DISORDERS (WAD): BIOBEHAVIORAL APPROACH

颈椎扭伤相关疾病 (WAD) 的治疗：生物行为方法

• 批准号: 7603434
• 负责人: DENNIS Charles TURK
• 金额: $ 0.53万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-04-01 至 2007-09-16
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7603434
• 关键词: Anxiety; Back Pain; Caring; Chronic; Clinical; Clinical Trials; Computer Retrieval of Information on Scientific Projects Database; Disease; Early Intervention; Emotional; Fright; Functional disorder; Funding; Grant; Injury; Institution; Intervention; Maintenance; Minor; Musculoskeletal Pain; Neck Injuries; Outcome; Pain; Police; Purpose; Reporting; Research; Research Personnel; Resistance; Resources; Risk; Source; Staging; Standards of Weights and Measures; Symptoms; Target Populations; Testing; United States; United States National Institutes of Health; Whiplash Injuries; base; biobehavior; chronic pain; disability; experience; lectures; prevent; response; vehicular accident

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Over 6.1 million police-reported motor vehicle accidents (MVAs) occurred in the United States in 2000. Whiplash injury is the most common form of injury resulting from an MVA. People prone to negative emotional responses are at risk of experiencing elevated levels of fear and anxiety and consequently may be predisposed to develop Whiplash-Associated Disorders (WADs), the clinical manifestations of whiplash injury. Chronic WADs (those that last longer than 6 months) are extremely resistant to treatment. Little is known about the pathophysiology of chronic WADs due to relatively minor neck injury following MVAs. Early interventions in back pain populations that target reduction of fear and subsequent avoidance of activity have been shown to prevent chronic musculoskeletal pain and disability. Preventing chronicity of WADs using similar interventions, however, has not been explored. The purpose of this clinical trial is to test the efficacy of early, biobehavioral interventions to prevent chronic pain and disability associated with whiplash injuries following an MVA. The study compares the efficacy of two interventions in reducing pain and disability at the subacute stage, thus preventing maintenance of WAD symptoms compared to standard care. We hypothesize that (1) intervention subjects will demonstrate significantly greater reduction of anxiety, pain, and functional limitations than standard care subjects, (2) an intervention using exposure-based anxiety reduction will result in significantly better outcomes than an intervention using educational lectures, and (3) subacute WAS subjects will report significantly greater degrees of anxiety and fear-avoidance than subjects whose symptoms remit within 1 month following the MVA.

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