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中文摘要
翻译
这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金, 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 这是一项随机、双盲、安慰剂对照、序贯剂量递增研究,旨在评估西多福韦对新诊断为BK病毒引起的肾病(肾脏疾病)的肾移植受者的安全性、耐受性、最大耐受量、身体影响和初步疗效。西多福韦VISTIDE是一种针对艾滋病毒感染患者的巨细胞病毒病的上市产品。
英文摘要
This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This is a randomized, double-blind, placebo-controlled, sequential dose escalation study to evaluate the safety, tolerability, maximum tolerance dose, physical affects and preliminary effectiveness of cidofovir in kidney transplant recipients with newly diagnosed BK virus-induced nephropathy (kidney disorder). Cidofovir VISTIDE is a marketed product for cytomegalovirus disease in HIV-infected patients.
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