MATERNAL AND INFANT BODY COMPOSITION AND RESTING ENERGY EXPENDITURE

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 孕妇在怀孕期间体重增加能够在两个关键方面影响发病率。怀孕期间体重增加不足通常会导致婴儿体型较小、健康状况不佳，而体重增加过多会使母亲和孩子长期肥胖及其共病。目前，体重增加10-12公斤被认为对大多数女性来说是合适的。这些建议是基于母亲孕前的营养状况和体重与身高的比例。尽管确保婴儿健康的最佳母亲体重增加的参数已经确立，但关于这些增加的构成以及它们如何影响婴儿的身体成分，人们知之甚少。因此，这项研究的主要重点将是检查怀孕期间(产后6-7周)和产后一年的产妇身体成分，因为它与非裔美国人和欧洲裔美国妇女的婴儿身体成分和生长发育指标(即体重、身高、头围和皮褶尺寸)有关。静息能量消耗(REE)是与脱脂体重相关的一个因素，也将在母亲和她们的婴儿身上进行检查。身体成分评估将使用双能X射线吸收法(DEXA)，稀土元素将使用Deltrac监测系统进行评估。这项初步研究将有助于为这一领域的进一步探索提供证据，并将被用来证明申请NIH拨款(PHS 416-1拨款)是合理的。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Maternal weight gain durng pregnancy has the ability to impact the incidence of morbidity in two crucial ways. Inadequate weight gains during pregnancy generally result in smaller and less healthy infants, while excessive gains predispose both the mother and the child to long-term obesity and its co-morbidities. Currently, weight gains between 10-12 kg are thought to be appropriate for most women. These recommendations are based upon the mother's pre-pregnancy nutritional and weight-for-height status. Although the parameters for optimal maternal weight gain to insure the good health of the infant are well established, little is known regarding the composition of those gains and how they impact the body composition of the infant. Therefore, the primary focus of this study will be to examine maternal body composition as a result of pregnancy (between 6-7 weeks postpartum) and at one year postpartum, as it relates to the infant's body composition and measures of growth and development (i.e. weight, length, head circumference, and skinfold measures)in African American and European American women. Resting energy expenditures (REE), which is a factor associated with fat-free mass, will also be examined in both the mothers and their infants. Body composition assessment will be achieved using dual energy x-ray absorptiometry (DEXA) and REE will be assessed using the Deltrac monitoring system. This pilot study will be instrumental inproviding substantiation for further exploration in this area, and will be used to justify a request for NIH grant funding (PHS 416-1 Grant).