MATERNAL AND INFANT BODY COMPOSITION AND RESTING ENERGY EXPENDITURE

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 中心，不一定是研究者的机构。 孕妇在怀孕期间体重增加有能力影响发病率在两个关键方面。 怀孕期间体重增加不足通常会导致婴儿更小和更不健康，而体重增加过多则会使母亲和婴儿容易患上长期肥胖症及其并发症。 目前，体重增加10 - 12公斤被认为是适合大多数妇女。 这些建议是基于母亲怀孕前的营养和身高体重状况。 虽然最佳母体体重增加的参数，以确保婴儿的良好健康是很好的建立，很少有人知道这些增益的组成，以及它们如何影响婴儿的身体组成。 因此，本研究的主要重点将是检查妊娠（产后6 - 7周）和产后1年时的母体身体组成，因为它与非洲裔美国人和欧洲裔美国人妇女的婴儿身体组成和生长发育指标（即体重、身长、头围和皮褶测量）有关。 静息能量消耗（REE），这是一个与无脂肪质量相关的因素，也将在母亲和他们的婴儿进行检查。 将使用双能X线吸收法（DEXA）进行身体成分评估，并使用Deltrac监测系统评估REE。 这项试验性研究将有助于为这一领域的进一步探索提供证据，并将用于证明申请NIH赠款资金（PHS 416 - 1赠款）的合理性。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Maternal weight gain durng pregnancy has the ability to impact the incidence of morbidity in two crucial ways. Inadequate weight gains during pregnancy generally result in smaller and less healthy infants, while excessive gains predispose both the mother and the child to long-term obesity and its co-morbidities. Currently, weight gains between 10-12 kg are thought to be appropriate for most women. These recommendations are based upon the mother's pre-pregnancy nutritional and weight-for-height status. Although the parameters for optimal maternal weight gain to insure the good health of the infant are well established, little is known regarding the composition of those gains and how they impact the body composition of the infant. Therefore, the primary focus of this study will be to examine maternal body composition as a result of pregnancy (between 6-7 weeks postpartum) and at one year postpartum, as it relates to the infant's body composition and measures of growth and development (i.e. weight, length, head circumference, and skinfold measures)in African American and European American women. Resting energy expenditures (REE), which is a factor associated with fat-free mass, will also be examined in both the mothers and their infants. Body composition assessment will be achieved using dual energy x-ray absorptiometry (DEXA) and REE will be assessed using the Deltrac monitoring system. This pilot study will be instrumental inproviding substantiation for further exploration in this area, and will be used to justify a request for NIH grant funding (PHS 416-1 Grant).