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Epidemiologic and Basic Science in Cancer Prevention

癌症预防的流行病学和基础科学

基本信息

批准号：
7293553
负责人：
James Marshall
金额：
$ 42.86万
依托单位：
ROSWELL PARK CANCER INSTITUTE CORP
依托单位国家：
美国
项目类别：
财政年份：
2006
资助国家：
美国
起止时间：
2006-09-29 至 2011-08-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/7293553
关键词：
Address Advisory Committees Affect American Association of Cancer Research Animals Anthropology Applications Grants Appointment Area Arizona Awareness Back Basic Science Beta-N-Acetylglucosaminidase Biochemistry Biological Markers Biometry Breast Cancer Prevention Breast Diseases Budgets Buffaloes Cancer Biology Cancer Control Cancer Etiology Cancer Immunology Science Cancer Prevention Intervention Carcinogens Cellular biology Chemoprevention Chemopreventive Agent Chemotherapy-Oncologic Procedure Chronic Disease Clinic Clinical Clinical Chemoprevention Clinical Research Clinical Sciences Clinical Trials Collaborations Colorado Communication Computers Conflict of Interest Consumption Critiques Data Data Set Depth Development Development Plans Diagnosis Discipline Discipline of Nursing Disease Division of Cancer Prevention Doctor of Philosophy Drug Metabolic Detoxication Early Diagnosis Education Educational Curriculum Educational process of instructing Educational workshop End Point Environmental Exposure Environmental Impact Enzymes Epidemiologic Methods Epidemiologic Studies Epidemiologist Epidemiology Ethics Etiology Evaluation Exposure to Faculty Fellowship Fertilization Foundations Functional disorder Funding Funding Agency Future Generations Genes Genetic Genetic Polymorphism Genetic Predisposition to Disease Genetic Processes Goals Grant Grant Review Group Meetings Growth Hawthorn plant Head Head and neck structure Health Health Occupations Health Professional Hormones Human Immunology Individual Institutes Institution Interdisciplinary Study Intervention Joints Laboratories Laboratory Research Laboratory Study Lead Leadership Learning Left Letters Libraries Link Literature Lung diseases Malignant - descriptor Malignant Neoplasms Malignant neoplasm of appendix Malignant neoplasm of lung Malignant neoplasm of prostate Marshal Mediation Medical Medicine Mentors Mentorship Metabolism Metastatic Prostate Cancer Methods Michigan Minor Mission Modeling Modification Molecular Molecular Biology Molecular Epidemiology Monitor Mutation Names National Cancer Institute Nature Neck Disorder Nutritionist Oxidative Stress Paper Participant Pathology Peroxidase Pharmaceutical Preparations Pharmacology Pharmacology and Toxicology Phase Physicians Policies Population Population Sciences Populations at Risk Postdoctoral Fellow Postmenopause Precancerous Conditions Predisposition Prevention Prevention Research Prevention program Preventive Preventive Medicine Principal Investigator Procedures Process Program Reviews Progress Reports Prostate-Specific Antigen Psychology Public Health Schools Publications Purpose Range Recording of previous events Recruitment Activity Reporting Research Research Design Research Ethics Committees Research Misconduct Research Personnel Research Project Grants Resources Risk Risk-Taking Roswell Park Cancer Institute Schedule Science Scientist Screening procedure Selenium Selenomethionine Seminal Series Services Smoking Structure Students Supplementation Surgical Oncology Surrogate Endpoint System Tamoxifen Teaching Materials Techniques Testing Therapeutic Time Tobacco Dependence Today Toxic effect Toxicogenetics Toxicology Training Training Programs Translating Translational Research Translations Travel Treatment Failure United States National Institutes of Health Universities Variant Vision Week Woman Work Writing addiction base behavioral/social science bench to bedside cancer epidemiology cancer genetics cancer immunology function cancer prevention cancer site cancer therapy carcinogenesis career catalase chemotherapeutic agent chemotherapy clinical application concept day disorder risk experience forging fruits and vegetables genetic epidemiology innovation interdisciplinary collaboration interest lectures malignant breast neoplasm medical schools member methaneselenol novel strategies oncology post-doctoral training pre-doctoral prevent programs research study skills smoking cessation social sociology/anthropology sound statistics success sulfotransferase thiol S-methyltransferase tool

项目摘要

DESCRIPTION (provided by applicant): Our vision of cancer prevention at Roswell Park Cancer Institute (RPCI) extends the "bench to bedside" paradigm of translational research to a "bench to sidewalk" model integrating basic bench, epidemiologic and population sciences. We maintain that prevention demands the translation of basic science as much as cancer treatment does. The goal of this R25T program, based in the division of Cancer Prevention and Population Sciences at RPCI, is to teach four postdoctoral fellows to develop the ability for interdisciplinary collaboration in cancer prevention research based on the "bench to sidewalk" model. Recruitment will be from fields such as epidemiology, anthropology, biochemistry, genetics, molecular biology, medicine, nursing and pathology. Potential fellows will maintain grounding in their core disciplines while reaching beyond those disciplines to forge interdisciplinary collaborations. This will be achieved through the development of a specialized curriculum, other didactic experiences, and in-depth research. To encourage this juxtaposition of disciplines, trainees will work with a primary mentor and one or more secondary mentors in a discipline distinct from but complimentary to that of the primary mentor and trainee. One trainee will be recruited in Year 01 for a three year fellowship. The program will be under the leadership of James Marshall, PhD, the Senior Vice President for Cancer Prevention and Population Sciences at RPCI. This program builds on RPCI's existing strengths: an established history of multidisciplinary collaboration; a strong group of mentors with numerous funded research projects; and a collaborative relationship with the University at Buffalo. The highly interdisciplinary Cancer Prevention program at RPCI is comprised of a diverse group of epidemiologists, nutritionists, basic scientists, and physicians with a strong record of intra-programmatic, and increasingly inter-programmatic, collaboration. This training program, with strong commitment from the faculty, will provide trainees from disparate scientific disciplines the opportunity to take advantage of broad-based expertise in epidemiology, genetics, biochemistry and cell biology, carcinogenesis, chemoprevention, and clinical science. A model for the collaboration we will develop is that between the epidemiologist/social scientist PI, Dr. Marshall, and the biochemist/molecular biologist Co-PI, Dr. Clement Ip.

描述（由申请人提供）：我们在罗斯威尔公园癌症研究所（RPCI）的癌症预防愿景将转化研究的“从实验台到床边”范式扩展到“从实验台到人行道”模式，整合了基础实验、流行病学和人口科学。我们坚持认为，预防需要基础科学的转化，就像癌症治疗一样。