Clinical Nutrition Research Unit

临床营养研究室

• 批准号: 7333085
• 负责人: ALAN CHAIT
• 金额: $ 38.12万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-09-01 至 2012-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7333085
• 关键词: Allied Health Profession; Animals; Area; Arts; Atherosclerosis; Basic Science; Biological Assay; Body Composition; Body Weight; Body measure procedure; Chronic Disease; Clinical; Clinical Investigator; Clinical Nutrition; Clinical Research; Collaborations; Core Facility; Diabetes Mellitus; Diet; Discipline; Disease; Education; Effectiveness; Energy Metabolism; Environment Design; Fostering; Genetic; Goals; Health; Interdisciplinary Study; Knowledge; Lipids; Medical Students; Mission; Nature; Numbers; Nutrient; Nutritional; Nutritional Study; Obesity; Patients; Physicians; Physiology; Productivity; Regulation; Research; Research Activity; Research Personnel; Resources; Rodent; Schools; Scientist; Series; Services; Students; Universities; Visit; Washington; base; cost; day; effectiveness research; gene interaction; human study; human subject; improved; interest; method development; mouse model; multidisciplinary; nutrition; nutrition education; programs; response

The major goal of the Clinical Nutrition Research Unit (CNRU) at the University of Washington is to promote and enhance interdisciplinary nutrition research by bringing together basic science and clinical investigators on a cooperative basis. Because of the multidisciplinary nature of nutrition, close interaction across disciplines and optimal use of resources is necessary to better understand the relationships among diet, health and disease states. By providing a number of Core facilities, the CNRU integrates and coordinates research activities in the field of nutrition and aims to foster new interdisciplinary research collaboration, stimulate new research activities, improve nutrition education at multiple levels and facilitate the nutritional management of patients. The four Cores are: 1) an Animal Studies Core, the Physiology Component of which measures body composition and energy expenditure in rodents, and a Genetic Component, which provides geneticallydefined mouse models for use in studies of nutrient-gene interactions; 2) an Analytic Core to provide Affiliate Investigators with cost-efficient state-of-the-art nutritional assays in both human subjects and experimental animals, and to help with new methods development; 3) a Human Studies Core to provide facilities and assistance for investigators with their clinical research, and 4) an Administrative and Enrichment Core that is responsible for the day-to-day administration of the CNRU. This Core also arranges a series of seminars, retreats, and Visiting Professorships, and administers the Pilot and Feasibility and New Investigator Programs. These programs are aimed at stimulating nutrition research by junior investigators and by more established investigators new to the field of nutrition in response to evolving research interests at the University of Washington. This Core also contains a biostatistical component that supports both basic and clinical research. Thus, the CNRU provides facilities and support for the large and varied nutrition research base of the University, which consists of 78 Affiliate Investigators. The major research foci of the University of Washington's CNRU are lipids and atherosclerosis, diabetes and body weight regulation, and obesity, i.e chronic diseases of major importance to the health of the nation. The presence of the CNRU at the University of Washington stimulates not only research, but also educational and clinical activities in the area of nutrition.

华盛顿大学临床营养研究小组(CNRU)的主要目标是 结合基础科学和临床，促进和加强跨学科的营养研究 调查人员在合作的基础上。由于营养学的多学科性质，密切互动 跨学科和资源的最佳利用对于更好地理解 饮食、健康和疾病状况。通过提供一系列核心设施，CNRU集成了 协调营养领域的研究活动，旨在促进新的跨学科研究 合作，激发新的研究活动，改善多层次的营养教育，促进 病人的营养管理。 这四个核心是：1)动物研究核心，其生理部分测量身体 啮齿动物的组成和能量消耗，以及遗传成分，它提供了基因定义的 用于研究营养-基因相互作用的小鼠模型；2)提供 联合研究人员在人类受试者和受试者中进行经济高效的最先进的营养分析 实验动物，并帮助开发新的方法；3)人类研究核心，提供 为研究人员的临床研究提供设施和协助，以及4)行政和 负责CNRU日常管理的浓缩核心。此核心也 安排一系列研讨会、务虚会和客座教授，并管理试点和 可行性和新的调查员计划。这些计划旨在通过以下方式刺激营养研究 初级调查人员和营养领域新手的更成熟的调查人员对 华盛顿大学不断发展的研究兴趣。这个核心还包含一个生物统计学 支持基础和临床研究的组件。 因此，CNRU为中国庞大而多样的营养研究基地提供了设施和支持 大学，由78名附属调查人员组成。加州大学的主要研究重点 华盛顿的CNRU是血脂和动脉粥样硬化，糖尿病和体重调节，以及肥胖，即 对国民健康有重大影响的慢性病。CNRU出现在 华盛顿大学不仅刺激研究，还鼓励教育和临床活动 营养领域。