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Metabolic Consequences of Thymidine Sparing Regimens

Metabolic Consequences of Thymidine Sparing Regimens
胸苷保留方案的代谢后果
批准号：
7332256
负责人：
GRACE A MCCOMSEY
金额：
$21.27万
依托单位：
CASE WESTERN RESERVE UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2006
资助国家：
美国
项目状态：
已结题
起止时间：
2006-01-01 至 2010-12-31
来源：
https://reporter.nih.gov/project-details/7332256
关键词：
8-Oxo-2&apos-DeoxyguanosineAIDS clinical trial groupAcquired Immunodeficiency SyndromeAdherenceAdipocytesAdipose tissueAdverse eventAffectAffinityAnti-Retroviral AgentsApoptosisBiological AssayBiological MarkersBiopsyBlindedBody CompositionBody fatCharacteristicsChronic DiseaseClinicalClinical TrialsComplicationConsequences of HIVControl GroupsControlled Clinical TrialsCoronary ArteriosclerosisCultured CellsDNA FragmentationDNA NucleotidylexotransferaseDNA-Directed DNA PolymeraseDataDigoxigeninDisincentiveDistressDual-Energy X-Ray AbsorptiometryElectron TransportElevationEnd PointEnrollmentF2-IsoprostanesFaceFatty acid glycerol estersFundingGoalsHIVHIV InfectionsHIV therapyHIV-1ImmunohistochemistryIncidenceLabelLaboratoriesLaboratory StudyLamivudineLeadLegLimb structureLipoatrophyLong-Term EffectsLongitudinal StudiesMeasurementMetabolicMitochondriaMitochondrial DNAMitochondrial ProteinsMorbidity - disease rateNumbersOxidative PhosphorylationOxidative StressParentsPathogenesisPatientsPharmaceutical PreparationsPhysiciansPloidiesPolymerase Chain ReactionPreventionPrintingQuality of lifeReactive Oxygen SpeciesRecommendationResearch PersonnelResearch Project GrantsResourcesReverse Transcriptase InhibitorsRiskRoleSafetyScanningSiteStavudineTenofovirTestingThymidineTimeToxic effectTreatment ProtocolsUnited States National Institutes of HealthUpdateUpper armVertebral columnWeekWorkZidovudineabacaviranalogantiretroviral therapydesignemtricitabineindexingmitochondrial dysfunctionnucleoside analogpreventprospectivesubcutaneous

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