CELL DIVISION GROUP RESEARCH

细胞分裂组研究

• 批准号: 7357340
• 负责人: EDWARD D. SALMON
• 金额: $ 0.12万
• 依托单位: MARINE BIOLOGICAL LABORATORY
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-12-01 至 2006-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7357340
• 关键词: CELL; DIVISION; GROUP; RESEARCH

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The BRC maintains one of two culture facilities available at the MBL and perhaps the best maintainted and equipped. We provide access to this facility on a limited basis to visitors not using our specialised resources. Salmon's group is one such example. They make summer use of the BRC cell culture facilities. Their research has for some years focused on the mechanisms behind spindle formation and control in cell growth. This summer saw the use of the facility to propagate PtK1 tissue cells expressing spindle checkpoint proteins Mad2 and Cdc20 fused to GFP. The cells were used in several different collaborative experiments with members of the Cell Division Group.

该子项目是利用NIH/NCRR资助的中心赠款提供的资源的许多研究子项目之一。子项目和研究者（PI）可能从另一个NIH来源获得主要资金，因此可以在其他CRISP条目中表示。所列机构为中心，不一定是研究者所在机构。BRC拥有MBL的两个文化设施之一，也许是设备和装备最好的。我们提供访问这个设施在有限的基础上不使用我们的专业资源的游客。Salmon的团队就是这样一个例子。他们夏季使用BRC细胞培养设施。多年来，他们的研究重点是细胞生长中纺锤体形成和控制背后的机制。今年夏天，该设施用于繁殖表达纺锤体检查点蛋白Mad 2和Cdc 20融合到GFP的PtK 1组织细胞。这些细胞被用于与细胞分裂小组成员的几个不同的合作实验中。