Regulation of sulphur partitioning between primary and secondary metabolism

初级和次级代谢之间硫分配的调节

• 批准号: BB/D009596/1
• 负责人: Stanislav Kopriva
• 金额: $ 34.35万
• 依托单位: John Innes Centre
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2006
• 资助国家: 英国
• 起止时间: 2006 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=BB%2FD009596%2F1
• 关键词: Regulation; sulphur; partitioning; between; primary

In the last two decades we have made great progress in improving our air quality by reducing emissions, e.g. of sulphur dioxide. As a consequence, however, less sulphur is falling naturally onto the Earth`s surface and there is a lack of sulphur in the soil. This has become a serious problem for UK agriculture. Sulphur is essential for all living organisms as it is bound in proteins and found in many other compounds vital for life. To make such compounds, plants need to take up sulphate from the soil, reduce it, and incorporate it into amino acids. In addition to these 'primary' compounds, plants synthesize a great variety of other biologically active 'secondary' molecules that are responsible for scent, colour, or the taste of plants. They also help in the defence of the plants against insects, fungi, or bacteria. Some crops, such as oilseed rape, produce a lot of these secondary compounds and therefore require more sulphur for their growth than other plants. We want to know how plants divide the sulphur they take up between the primary and secondary products. We will concentrate on one family of proteins that we believe are responsible for control of sulphur flow. We will create plants where these proteins will no longer be active and plants which will have much more of them. Comparing such plants will enable us to understand how the sulphur is divided between primary and secondary compounds. We want to test, whether plants that save sulphur by producing less of the secondary compounds will be as healthy as normal plants. The results of this project could allow us to develop crop plants that take up and use sulphur more efficiently, reducing the need for fertilisers.

在过去二十年，我们在改善空气质素方面，已取得重大进展，减少了二氧化硫等气体的排放。然而，其结果是，更少的硫自然地落在地球表面，土壤中缺乏硫。这已经成为英国农业的一个严重问题。硫对所有生物体都是必不可少的，因为它结合在蛋白质中，并存在于许多对生命至关重要的其他化合物中。为了制造这种化合物，植物需要从土壤中吸收硫酸盐，还原它，并将其转化为氨基酸。除了这些“初级”化合物，植物还合成了大量其他生物活性的“次级”分子，这些分子负责植物的气味，颜色或味道。它们还有助于植物抵御昆虫，真菌或细菌。一些作物，如油菜，产生大量的次生化合物，因此比其他植物需要更多的硫来生长。我们想知道植物如何将它们吸收的硫在初级产品和次级产品之间分配。我们将集中在一个家庭的蛋白质，我们认为是负责控制硫流。我们将创造出这些蛋白质不再活跃的植物，以及含有更多蛋白质的植物。比较这些工厂将使我们能够了解硫是如何在初级和次级化合物之间分配的。我们想测试，通过减少次级化合物来节省硫的植物是否会像正常植物一样健康。该项目的结果可以使我们开发出更有效地吸收和利用硫的作物，减少对肥料的需求。

项目成果

Control of sulfur partitioning between primary and secondary metabolism in Arabidopsis.

• DOI: 10.3389/fpls.2012.00163
• 发表时间: 2012
• 期刊: Frontiers in plant science
• 影响因子: 5.6
• 作者: Kopriva S;Mugford SG;Baraniecka P;Lee BR;Matthewman CA;Koprivova A
• 通讯作者: Koprivova A