IDENTIFICATION OF THE SHE3P/MYO4P-COMPLEX

本子项目是利用由NIH/NCRR资助的中心赠款提供的资源的众多研究子项目之一。子项目和研究者（PI）可能已经从另一个NIH来源获得了主要资金，因此可以在其他CRISP条目中表示。列出的机构是中心的，不一定是研究者的机构。在酿酒酵母中，基于肌动蛋白的V类肌球蛋白Myo4p及其相互作用伙伴She3p是内质网相关机制的一部分，这是皮质内质网遗传所必需的。我们感兴趣的是确定这一机制的组成部分并发现其规则。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. In Saccharomyces cerevisiae the actin based class V myosin Myo4p and its interaction partner, She3p, are part of an ER-associated machinery that is required for inheritance of the cortical ER. We are interested in identifying the components of this machinery and discovering its regulation.