SLEEP LOSS IN PATIENTS WITH ATOPIC DERMATITIS

这个子项目是利用由NIH/NCRR资助的中心拨款提供的资源的许多研究子项目之一。子项目和调查员(PI)可能从另一个NIH来源获得了主要资金，因此可能会出现在其他CRISE条目中。列出的机构是针对中心的，而不一定是针对调查员的机构。特应性皮炎患者经常有睡眠困难，尽管在这一组中进行的关于睡眠的研究很少。我们试图通过让一组患有特应性皮炎的成年人在国家犹太人睡眠研究中心睡两晚来记录他们的睡眠情况。两个晚上是必要的，因为当一个人第一次在陌生的睡眠实验室环境中睡觉时，可能会干扰睡眠。两个晚上都会进行全面的多导睡眠监测，测量人的睡眠细节，但我们将重点放在第二个晚上的睡眠测量上。我们还将使用一种名为活动记录仪的设备记录睡眠情况，与多导睡眠记录仪相比，该设备提供了一种简单的睡眠测量方法，可以戴在手腕上。最后，患者将完成关于他们睡眠质量以及睡眠质量差如何影响他们生活的问卷调查。这项研究的结果将有助于我们更好地描述特应性皮炎患者的睡眠特征，并将使我们能够在未来的特应性皮炎研究中确定用于测量实验室外睡眠的活动记录仪的有效性。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Patients with atopic dermatitis often have trouble sleeping, although few studies of sleep in this group have been conducted. We are seeking to document sleep in a group of adults with atopic dermatitis by having them sleep in the National Jewish Sleep Research Unit for two nights. Two nights are necessary because of the interference with sleep that can occur the first time a person sleeps in the unfamiliar setting of the sleep laboratory. Full polysomnography, which measures details about how the person is sleeping, will be conducted both nights, but we will focus upon the sleep measurements from night two. We are also going to document sleep with a device called an actigraph, which provides a simple measure of sleep compared to polysomnography, and is worn on the wrist. Finally patients will complete questionnaires about how well they slept and how poor sleep has affected their lives. Results from this study will help us better characterize sleep in patients with atopic dermatitis, and will allow us to ascertain the validity of the actigraph for measurement of sleep outside the laboratory in future atopic dermatitis studies.