NSABP B-27:TRIAL COMPARING PREOP AC TO AC FOLLOWED BY TAXOTERE/CANCER OF BREAST

NSABP B-27：比较术前 AC 与随后使用泰索帝/乳腺癌的 AC 的试验

• 批准号: 7376234
• 负责人: EUGENE A WOLTERING
• 金额: $ 0.04万
• 依托单位: TULANE UNIVERSITY OF LOUISIANA
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-12-01 至 2006-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7376234
• 关键词: NSABP; 27; TRIAL; COMPARING; PREOP

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The primary aim of this study to determine whether 4 cycles of preoperative or postoperative Taxotere given after 4 cycles of preoperative AC will more effectively prolong disease-free survival and survival than do 4 cycles of pre-operative AC alone. This study will also evaluate the effect of the administration of pre-operative Taxotere after preoperative AC with respect to clinical and pathologic loco-regional tumor response and breast conservation.

该子项目是利用NIH/NCRR资助的中心赠款提供的资源的许多研究子项目之一。子项目和研究者（PI）可能从另一个NIH来源获得主要资金，因此可以在其他CRISP条目中表示。所列机构为中心，不一定是研究者所在机构。本研究的主要目的是确定4个周期的术前AC后给予4个周期的术前或术后泰索帝是否比4个周期的术前AC单独治疗更有效地延长无病生存期和生存期。本研究还将评价术前AC后术前泰索帝给药对临床和病理局部肿瘤缓解和乳腺保护的影响。