ANGIOGENIC ENDOTHELIAL CELL DETECTION IN PERIPHERAL CIRCULATION IN METASTATIC DS

本子项目是利用由NIH/NCRR资助的中心赠款提供的资源的众多研究子项目之一。子项目和研究者（PI）可能已经从另一个NIH来源获得了主要资金，因此可以在其他CRISP条目中表示。列出的机构是中心的，不一定是研究者的机构。这是一项自愿的研究，目的是观察简单的血液测试是否能检测出血液中可能只由癌细胞血管产生的基因。大约60名受试者将被纳入本研究。将有三组科目。将有20名受试者由健康个体组成，20名癌症患者已经从身体的一个部位扩散到另一个部位，20名受试者将接受一种名为Octreother的研究药物的治疗。前两组受试者一次将捐献大约5cc的血液。接受Octreother治疗的受试者将在治疗前捐献约5cc血液，每次治疗后捐献1毫升血液（最多3茶匙）。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This is a voluntary research study to see if a simple blood test can detect the presence of a gene in the blood which may be produced only by cancer cell blood vessels. Approximately 60 subjects will be enrolled into this study. There will be three groups of subjects. There will be 20 subjects that will consist of healthy individuals, 20 subjects with cancer that has spread from one area to another in the body and 20 subjects will be receiving treatment with a study drug called Octreother. Subjects in the first two groups will donate approximately 5cc of blood on one occasion. Subjects undergoing treatment with Octreother will donate approximately 5cc of blood prior to treatment and one after each treatment with Octreother (maximum three teaspoons).