METABOLIC EFFECTS OF GROWTH HORMONE UPON BODY COMPOSITION IN TODDLERS WITH PWS

生长激素对 PWS 幼儿身体成分的代谢影响

• 批准号: 7375485
• 负责人: AARON L CARREL
• 金额: $ 0.22万
• 依托单位: UNIVERSITY OF WISCONSIN-MADISON
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-12-01 至 2006-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7375485
• 关键词: METABOLIC; EFFECTS; GROWTH; HORMONE; UPON

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Prader-Willi syndrome (PWS) is a rare genetic disorder associated with obesity. Early in life, children with PWS demonstrate poor weight gain and low muscle tone. This study evaluates the effect of growth hormone (GH) upon these conditions. This randomized controlled study will compare children with PWS treated with GH compared to control PWS children. Outcomes will include measuring body fat, muscle mass, energy expenditure, hormonal levels an

该子项目是利用NIH/NCRR资助的中心赠款提供的资源的许多研究子项目之一。子项目和研究者（PI）可能从另一个NIH来源获得主要资金，因此可以在其他CRISP条目中表示。所列机构为中心，不一定是研究者所在机构。Prader-Willi综合征（PWS）是一种与肥胖相关的罕见遗传性疾病。在生命的早期，PWS儿童表现出体重增加不良和肌肉张力低。本研究评估了生长激素（GH）对这些条件的影响。这项随机对照研究将比较接受GH治疗的PWS儿童与对照PWS儿童。结果将包括测量身体脂肪，肌肉质量，能量消耗，荷尔蒙水平和