General Clinical Research Center

点击翻译按钮获取中文摘要

EXCEED THE SPACE PROVIDED. The University of Texas Health Science Center at Houston (UTHSC-H) requests continued support for the operation of the University Clinical Research Center (UCRC) at Memorial Hermann Hospital (MHH). The UTHSC - H is located in the Texas Medical Center (TMC), the largest Medical Center in the World. In operation since 1984, the UCRC continues to grow and be utilized by a wide diversity of investigators from the UTHSC - Medical School and 8 other institutions in the TMC. In 2003, projects from the MDAnderson Cancer Center, the Texas Heart Institute andthe UTHSC- H School of Nursing, School of Public Health, the Brown Institute for Molecular Medicine, Dental Branch, Mental Sciences Institute and the Graduate School of Biological Sciences represented 16% of our protocols and utilized 26% of our ancillaries' budget. When compared to our previous competitive renewal, we have increased the number of visits by 75%, and doubled the number of approved protocols and publications. With the support of MHH, a new UCRC with twice the capacity will be operational in the winter of 2004. Continued funding will enable us to conduct novel studies to understand and treat aortic aneurysms, neonatal hyperbilirubinemia, Ewing's sarcoma, infectious diarrhea due to enteroaggregative E. coli, diabetes in children and their families, autoimmune disorders such as scleroderma, and clinically significant obesity, among other clinical research projects that are ongoing or planned. Support is also requested to a) Continue the operations of our genotyping and sequencing core laboratory at the UCRC, b) Support a cooperative effort of the 5 GCRCs in Texas to conduct off site clinical research in the Lower Rio Grande Valley (LRGV) in South Texas. This facility will host regional projects developed by local investigators in the LRGV region as well as for new and existingprojects from all GCRCs in Texas and in the future other GCRCs located out of Texas. This model will allow ei'fective utilization of resources and provide access to patient oriented clinical research for a traditionallyunderserved Hispanic population with health access disparities c) Continue the Clinical Research Feasibility Funds program, and d) Continue the UTHSC - H UCRC Mentored Medical Student Research Program.