PACTG P1025 PHARMACOKINETIC PROPERTIES OF ANTIRETROVIRAL DRUGS DURING PREGNANCY

本子项目是利用由NIH/NCRR资助的中心赠款提供的资源的众多研究子项目之一。子项目和研究者（PI）可能已经从另一个NIH来源获得了主要资金，因此可以在其他CRISP条目中表示。列出的机构是中心的，不一定是研究者的机构。评估为预防艾滋病毒垂直传播和/或妇女健康规定的干预措施的有效性。评估为妇女健康和/或预防艾滋病毒垂直传播而规定的干预措施的母婴安全性。为深入的子研究提供框架和标本库，旨在进一步阐明艾滋病毒垂直传播的危险因素和机制，以及影响母婴结局的因素。评估感染艾滋病毒的孕妇在怀孕和产后坚持接受抗逆转录病毒治疗的情况及其对妇女健康和垂直传播的影响，并评估婴儿坚持接受化学预防治疗的情况。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Assess the effectiveness of interventions prescribed for prevention of vertical transmission of HIV and/or for women's health. Assess maternal and infant safety of interventions prescribed for women's health and/or prevention of vertical transmission of HIV. Provide framework and specimen repository for intensive substudies that aim to further elucidate risk factors for and mechanisms of vertical transmission of HIV as well as factors that affect maternal and infant outcomes. Assess adherence to ART among HIV-infected pregnant women during pregnancy and postpartum and its impact on women's health and vertical transmission and to assess adherence to chemoprophylaxis in infants.