课题基金 / 基金详情

MEDICINAL CANNABIS IN PAINFUL HIV NEUROPATHY

MEDICINAL CANNABIS IN PAINFUL HIV NEUROPATHY
药用大麻治疗痛苦的艾滋病毒神经病
批准号:
7374159
负责人:
RONALD J. ELLIS
金额:
$12.9万
依托单位国家:
美国
项目类别:
财政年份:
2006
资助国家:
美国
项目状态:
已结题
起止时间:
2006-04-01 至 2006-11-30

项目摘要

项目成果

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中文摘要
翻译
这个子项目是利用由NIH/NCRR资助的中心拨款提供的资源的许多研究子项目之一。子项目和调查员(PI)可能从另一个NIH来源获得了主要资金,因此可能会出现在其他CRISE条目中。列出的机构是针对中心的,而不一定是针对调查员的机构。确定用于治疗HIV相关的远端感觉型多发性神经病的神经病理性疼痛的药用大麻作为短期止痛剂的安全、临床有用和有效的剂量范围。确定与短期使用大麻用于止痛有关的不良反应的程度和临床意义,如认知障碍。
英文摘要
This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Ascertain a safe, clinically useful and efficacious dosing range for medicinal cannabis as a short-term analgesic in the treatment of neuropathic pain in HIV-associated distal, sensory-predominant polyneuropathy. Determine the magnitude and clinical significance of adverse effects such as cognitive impairment associated with short-term use of cannabis for analgesia.
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会议论文
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GPLD1: Association with Cognition and Amelioration through Exercise in Aging People with HIV
Effects of Cannabidiol and Tetrahydrocannabinol on the Microbiome, Endocannabinoids and Neuroinflammation in HIV
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