HALT-C TRIAL

该子项目是利用NIH/NCRR资助的中心赠款提供的资源的许多研究子项目之一。子项目和研究者（PI）可能从另一个NIH来源获得了主要资金，因此可以在其他CRISP条目中表示。所列机构为中心，不一定是研究者所在机构。慢性丙型肝炎是一种影响肝脏的长期病毒感染，可能导致永久性肝损伤，偶尔会导致肝癌。本研究的目的是确定使用PEG干扰素长期维持治疗（3-1/2年）的安全性和有效性，与既往治疗未能清除血液中病毒的慢性丙型肝炎感染受试者相比，无治疗。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Chronic hepatitis C is a long-lasting viral infection affecting the liver which may lead to permanent liver damage and, occasionally, to liver cancer. The purpose of this study is to determine the safety and efficacy of using long-term maintenance therapy (3-1/2 years) with PEG interferon compared to no treatment in subjects infected with chronic hepatitis C who have failed to clear virus from the bloodstream with previous courses of therapy.