VARIABILITY BETWEEN INDIVIDUALS WITH RESPECT TO COGNITIVE AND PHYSIOLOGICAL

个体之间在认知和生理方面的差异

• 批准号: 7375351
• 负责人: LILIANNE R MUJICA-PARODI
• 金额: $ 8.78万
• 依托单位: STATE UNIVERSITY NEW YORK STONY BROOK
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-12-01 至 2006-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7375351
• 关键词: VARIABILITY; BETWEEN; INDIVIDUALS; RESPECT; COGNITIVE

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The problem of emotional arousal and its cognitive consequences not only has short-term,sometimes irreversible ,neuro-toxic effects on the brain. These potential effects of stress need to be better understood both to minimize risk,as well as eventually to develop better treatment for damage that has already occurred. This study constitutes a critical first step in investigating both short and long-term effects of stress reactivity, using an inter-disciplinary approach combined with state of the art technology, to establish much needed norms on human performance and neurological function under arousal. The primary aims of this study are to: a) examine variability between individuals on neural,cardiac,and endocrine measures of stress reactivity; b) to investigate whether,for each individual,physiological stress reactivity accurately predicts that individual's cognitive resilience to arousal,as measured by pre-attentive and attentive utilization of relevant cues and screening of irrelevant cues; and c) to elucidate the role of compensatory neural mechanisms in those individuals who are most efficient at ameliorating the cognitive and physiological effects of arousal.

该子项目是利用NIH/NCRR资助的中心赠款提供的资源的许多研究子项目之一。子弹和调查员（PI）可能已经从其他NIH来源获得了主要资金，因此可以在其他清晰的条目中代表。列出的机构适用于该中心，这不一定是调查员的机构。情绪唤醒及其认知后果的问题不仅对大脑具有短期，有时是不可逆的神经毒性影响。需要更好地理解压力的这些潜在影响，以最大程度地降低风险，并最终为已经发生的损害开发更好的治疗方法。这项研究构成了使用跨学科反应性的短期和长期影响的重要第一步，使用跨学科的方法与最先进的技术结合使用，以建立急需的人类绩效和神经功能的规范。这项研究的主要目的是：a）检查个体在神经，心脏和内分泌量度的压力反应性测量方面的变异性； b）调查每个人是否会准确地预测个人对唤醒的认知韧性是否准确，这是通过对相关提示的前进和细心利用和筛查无关线索的筛查来衡量的； c）阐明那些在改善唤醒的认知和生理效应方面最有效的个体中补偿性神经机制的作用。