NON-INVASIVE STUDY OF CARDIOVASCULAR DISEASE IN HEMODIALYSIS PATIENTS

血液透析患者心血管疾病的非侵入性研究

• 批准号: 7376306
• 负责人: PAOLO none RAGGI
• 金额: $ 0.14万
• 依托单位: TULANE UNIVERSITY OF LOUISIANA
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-12-01 至 2006-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7376306
• 关键词: NON; INVASIVE; STUDY; CARDIOVASCULAR; DISEASE

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The aims of this proposed clinical protocol in chronic dialysis patients are to assess: 1. the presence and extent of aortic, coronary, and valvular calcification by Electron Beam Computed Tomography. 2. Abdominal aorta and iliac arteries calcification by plain abdomen and pelvic x-ray. 3. Left ventricular mass and systo-diastolic function by echocardiography. 4. Arterial stiffness of large compliance arteries by measuring Pulse Wave Velocity. 5. Bone mineral density of spine, hip and forearm as it relates to vascular calcifications. 6. Association of serological markers of disease with atherosclerosis prevalence and progression.

这个子项目是利用由NIH/NCRR资助的中心拨款提供的资源的许多研究子项目之一。子项目和调查员(PI)可能从另一个NIH来源获得了主要资金，因此可能会出现在其他CRISE条目中。列出的机构是针对中心的，而不一定是针对调查员的机构。在慢性透析患者中，这一拟议的临床方案的目的是评估：1。电子束计算机断层扫描显示主动脉、冠状动脉和瓣膜钙化的存在和范围。2.腹部平片和盆腔X线片显示腹主动脉和髂动脉钙化。3.超声心动图测定左心室重量和收缩-舒张期功能。4.用脉搏波速度测量大顺应性动脉的动脉硬度。5.脊柱、髋部和前臂骨密度与血管钙化的关系。6.疾病的血清标志物与动脉粥样硬化的发生和发展的关系。