RELAXATION AND HYPNOTIC TREATMENT OF DISABILITY-RELATED PAIN

这个子项目是利用由NIH/NCRR资助的中心拨款提供的资源的许多研究子项目之一。子项目和调查员(PI)可能从另一个NIH来源获得了主要资金，因此可能会出现在其他CRISE条目中。列出的机构是针对中心的，而不一定是针对调查员的机构。这项研究的目的是在294名残疾人(多达134名脊髓损伤患者和160名飞行员：20名截肢患者、40名多发性硬化症患者、20名脑瘫患者、20名神经肌肉疾病患者、20名脊髓灰质炎后综合征患者、20名中风后疼痛患者和20名神经病理性疼痛患者)中，研究两种放松和暗示程序对疼痛和疼痛干预的即刻和长期影响。患有脊髓损伤的研究参与者将被随机分配到两种治疗条件中的一种：(1)“放松1”，这是一种放松训练条件，将包括一些催眠常见的成分(侧重于视觉线索、放松建议)以及对感知止痛的建议；或(2)“放松2”，这是一种放松训练条件，将只包括催眠常见的一种成分(重点关注视觉线索)，外加减少肌肉紧张的生物反馈。患有多发性硬化症的初步研究参与者将被随机分配到两种治疗条件中的一种：(1)上述放松1条件，或(2)结合渐进性肌肉放松的传统放松训练条件。其余的试点参与者将参加上述放松1条件。主要结果变量(疼痛强度)和次要结果变量(疼痛干预、医疗服务利用、抑郁和感知的疼痛控制)都通过电话采访进行评估。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The purpose of this study is to examine the immediate and long-term effects of two relaxation and suggestion procedures on pain and pain interference relative to each other and to a no-treatment baseline (four or eight weeks in length, depending on the patient's condition) in a group of 294 individuals with disability (up to 134 with spinal cord injury, and 160 pilots: 20 with amputation, 40 with multiple sclerosis, 20 with cerebral palsy, 20 with neuromuscular disease, 20 with post-polio syndrome, 20 post-stroke patients with pain, and 20 with neuropathic pain) who report bothersome disability-related pain. Study participants with SCI will be randomly assigned to one of two treatment conditions: (1) "Relaxation 1" which is a relaxation training condition that will include some components common to hypnosis (focusing on a visual cue, suggestions for relaxation) as well as suggestions for perceived analgesia or (2) "Relaxation 2" which is a relaxation training condition that will include only one component common to hypnosis (focusing on a visual cue) plus biofeedback for reduction of muscle tension. Pilot study participants with MS will be randomly assigned to one of two treatment conditions: (1) the Relaxation 1 condition described above, or (2) a traditional relaxation training condition that incorporates progressive muscle relaxation. The rest of the pilot participants will be enrolled in the Relaxation 1 condition described above. The primary outcome variable (pain intensity) and secondary outcome variables (pain interference, medical services utilization, depression, and perceived pain control) are all assessed via telephone interviews.