DOES FLUOXETINE REVERSE THE EFFECTS OF EARLY LIFE STRESS ON THE CNS CRF SYSTEM

氟西汀是否可以逆转早期生活压力对 CNS CRF 系统的影响

• 批准号: 7376397
• 负责人: CHRISTINE M HEIM
• 金额: $ 0.37万
• 依托单位: EMORY UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-12-01 至 2006-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7376397
• 关键词: DOES; FLUOXETINE; REVERSE; EFFECTS; EARLY

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This study is an amendment to SPID 3881. The goal of this study is to determine whether fluoxetine (antidepressant) reverses the neurobiological consequences of early life stress (e.g., child abuse) and, thus, is effective for treatment and prevention of stress-related syndromal or subsyndromal psychopathology.

该子项目是利用 NIH/NCRR 资助的中心拨款提供的资源的众多研究子项目之一。子项目和研究者 (PI) 可能已从另一个 NIH 来源获得主要资金，因此可以在其他 CRISP 条目中得到体现。列出的机构是中心的机构，不一定是研究者的机构。本研究是对 SPID 3881 的修订。本研究的目的是确定氟西汀（抗抑郁药）是否可以逆转早期生活压力（例如虐待儿童）的神经生物学后果，从而有效治疗和预防与压力相关的综合征或亚综合征精神病理学。