EFFECT OF CITALOPRAM ON WORRY-INDUCED RCBF CHANGES

本子项目是利用由NIH/NCRR资助的中心赠款提供的资源的众多研究子项目之一。子项目和研究者（PI）可能已经从另一个NIH来源获得了主要资金，因此可以在其他CRISP条目中表示。列出的机构是中心的，不一定是研究者的机构。该研究增加了4名广泛性焦虑症患者，以增加样本，并对数据进行更好的统计分析。对10例广泛性焦虑症患者在西酞普兰治疗7周前后进行fMRI扫描。成像包括测量BOLD反应，而1。通过听到描述个人担忧的句子和情绪中立的句子来引起焦虑。一项决策任务，通过测量何时识别出模糊的图像。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The study added 4 patients with GAD to increase the sample and permit better statistical analysis of the data. Ten patients with GAD were scanned, using fMRI, before and after 7 weeks of treatment with citalopram. Imaging consisted in measuring BOLD responses while 1. inducing anxiety by hearing sentences that described a personal worry versus emotionally neutral sentences and 2.a decision making task, by measuring when a indistinctly drawn picture was recognized.