COGNITIVE, BEHAVIORAL AND PSYCHOSOCIAL CORRELATES OF MEDICATION ADHERENCE IN CHI

这个子项目是利用由NIH/NCRR资助的中心拨款提供的资源的许多研究子项目之一。子项目和调查员(PI)可能从另一个NIH来源获得了主要资金，因此可能会出现在其他CRISE条目中。列出的机构是针对中心的，而不一定是针对调查员的机构。PACTG 1042S是一项横断面研究，将在患有围产期获得性艾滋病毒感染的儿童和青少年中，将认知、行为和心理社会功能与抗逆转录病毒药物治疗的责任和坚持程度相关联。它还将把认知、行为和心理社会功能与病毒学抑制和免疫状态的衡量标准联系起来，并比较自我报告和服药依从性的衡量标准。这项研究预计将招募200名可评估的参与者。这项研究的人群包括8岁至19岁的围产期获得性HIV-1感染的儿童和青少年，他们参加了PACTG 219C并进行了积极的后续行动。研究分层分为两组：A组：12岁；B组：12岁。这是一项为期48周的研究。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. PACTG 1042s is a cross-sectional study that will correlate cognitive, behavioral, and psychosocial functioning with the degree of responsibility for and adherence to antiretroviral medication regimens in children and adolescents with perinatally acquired HIV infection. It will also correlate cognitive, behavioral and psychosocial functioning with measures of virologic suppression and immunological status, and compare self-report and pill count measures of adherence. The study anticipates enrolling 200 evaluable participants. The population for this study consists of children and adolescents with perinatally acquired HIV-1 infection 8 to <19 years of age, who are enrolled and in active follow-up in PACTG 219c. The study stratification consists of two groups: Group A: <12 years of age Group B: >=12 years of age. This is a forty-eight week study.