General Clinical Research Center

全科临床研究中心

• 批准号: 6963130
• 负责人: ROBERT J ALPERN
• 金额: $ 337.21万
• 依托单位: YALE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-04-01 至 2006-09-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6963130
• 关键词: clinical research; human subject

EXCEED THE SPACE PROVIDED. This competitive renewal application (RR00125) requests continued support for the Yale General Clinical Research Center (GCRC) that now includes the previously independent Children's Clinical Research Center (RR 06022) following the merge of the programs on 12/1/03. The goals of the new GCRC are to: increase services provided to investigators, competencies of research staff, the efficiency of operations, the quality of GCRC oversight and the diversity of research protocols (while maintaining traditional strengths in diabetes, metabolism, neuroscience, and psychiatry), as well as foster high quality clinical investigation and strengthen training and career development programs. Several new initiatives are proposed including Magnetic Resonance and Genomics Resource Cores and community-based nursing support. The GCRC inpatient and outpatient units and most of the GCRC staff are housed in the recently renovated 10- 5 and 10-6Units of the Yale-New Haven Hospital. Switching to a per diem method of reimbursement has reduced inpatient costs. Continued support is requested for Nursing Personnel, the Core Laboratory, Informatics, Biostatistics, Bionutrition, and the CReFF program. The commitment to protection of research subjects requires the efforts of GCRC Research Subject Advocates and improved communication and coordination with the Human Investigation Committee (HIC). The GCRC serves as a valuable resource for trainees enrolled in 23 T32 post-doctoral fellowship programs, the Investigative Medicine (K30)doctoral program, the Robert Wood Johnson Program, and the NCRR-supported K12 program, as well as K23 and K24 awardees. Finally, Yale has in place a large body of clinical research that requires and is enhanced by GCRC support. The 118 protocols described in this application come from a broad range of clinical investigators with diverse interests that involve research subjects from premature infants to the elderly. This GCRC- based research is supported by peer reviewed grants that total ~$33 million of which ~94%are NIH funded. The central role of GCRC clinical research programs at the medical center is reflected by the strong and tangible commitments that the new Dean of the School of Medicine and Yale-New Haven Hospital leadership have made to our newly merged unit.

超出空间 提供了 本竞争性更新申请（RR 00125）要求继续支持耶鲁综合临床研究 中心（GCRC），现在包括以前独立的儿童临床研究中心（RR 06022）， 2003年1月12日的合并计划新的全球审查中心的目标是：增加向调查人员提供的服务， 研究人员的能力、业务效率、GCRC监督的质量和研究的多样性 协议（同时保持糖尿病，代谢，神经科学和精神病学的传统优势），以及 促进高质量的临床研究，加强培训和职业发展方案。几个新 提出的倡议包括磁共振和基因组学资源核心和社区护理 支持. GCRC住院部和门诊部以及大多数GCRC工作人员都住在最近翻修的10- 5和10- 6单位的耶鲁纽黑文医院。改用每日津贴偿还办法后， 住院费用。要求继续支持护理人员、核心实验室、信息学、生物统计学， 生物营养素和CReFF计划。保护研究受试者的承诺需要GCRC的努力 研究主题倡导者，并改善与人类研究委员会的沟通和协调 （HIC）。GCRC是参加23个T32博士后奖学金项目的学员的宝贵资源， 研究医学（K30）博士项目、罗伯特·伍德·约翰逊项目和NCRR支持的K12 以及K23和K24获奖者。最后，耶鲁大学有大量的临床研究， 并通过GCRC支持得到增强。本申请中描述的118个协议来自广泛的临床应用， 研究人员兴趣广泛，研究对象从早产儿到老年人。本GCRC- 基于基础的研究由同行评审的赠款支持，总额约为3300万美元，其中约94%由NIH资助。中央 GCRC临床研究项目在医疗中心的作用体现在其强有力的、切实的承诺上， 医学院的新院长和耶鲁-纽黑文医院的领导层对我们新合并的单位做出了贡献。