PACTG P1006: THE EFFECTS OF HIGHLY ACTIVE ANTIRETROVIRAL THERAPY (HAART)

这个子项目是利用由NIH/NCRR资助的中心拨款提供的资源的许多研究子项目之一。子项目和调查员(PI)可能从另一个NIH来源获得了主要资金，因此可能会出现在其他CRISE条目中。列出的机构是针对中心的，而不一定是针对调查员的机构。在开始高效抗逆转录病毒疗法(HAART)后，接受多种有效抗逆转录病毒药物治疗的HIV-1感染儿童的CD4细胞显著增加。尽管研究人员已经意识到HAART后免疫功能发生了几个变化，但还没有发表的大型研究来描述感染了hiv病毒的儿童免疫恢复的动态。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. HIV-1 infected children treated with multiple potent antiretrovirals have experienced a significant increase in CD4 cells after initiation of highly active antiretroviral therapy (HAART). Although researchers are aware there are several changes in the immune function following HAART, no large published studies have delineated the dynamics of immune recovery in HIV-infected ch