EPIDEMIOLOGY STUDY OF CONGENITAL HEART MALFORMATION

该子项目是利用NIH/NCRR资助的中心赠款提供的资源的许多研究子项目之一。子项目和研究者（PI）可能从另一个NIH来源获得了主要资金，因此可以在其他CRISP条目中表示。所列机构为中心，不一定是研究者所在机构。本研究的目的是了解环境因素是否与人类心脏畸形有关。这是一项关于大华盛顿地区心脏畸形可能危险因素的观察性研究。这项研究的总体假设是，基因-环境相互作用调节特定类型的人类心脏畸形的发生。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The purpose of this study is to see if environmental factors are associated with human heart malformations. This is an observational study of possible risk factors for heart malformations in the greater Washington DC area. The overall hypothesis of this study is that gene-environment interactions modulate the occurrence of specific types of human heart malformations.