EFFECTS OF AGE ON THE RESPONSE TO OXIDATIVE STRESS

点击翻译按钮获取中文摘要

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. We hypothesize that the extent to which levels of F2-isoprostanes, products of free radical mediated lipid peroxidation, increase in plasma following forearm ischemia/reperfusion induced by inflating and deflating a blood pressure cuff will provide an accurate assessment of an individual's total antioxidant capacity and that this is impaired in the elderly.