BREAST CANCER WALKING STUDY

这个子项目是利用由NIH/NCRR资助的中心拨款提供的资源的许多研究子项目之一。子项目和调查员(PI)可能从另一个NIH来源获得了主要资金，因此可能会出现在其他CRISE条目中。列出的机构是针对中心的，而不一定是针对调查员的机构。这项先导性研究的目标是：1)量化12周的居家步行干预和12周步行和饮食联合干预对乳腺癌幸存者的体力活动水平、健康状况、生活质量、身体成分和雌激素代谢的影响；2)开发和测试体力活动和饮食干预材料的可行性，以便在该人群中进行未来的研究。我们假设，随机接受步行干预的女性将报告更高的体力活动水平，以及身体状况的生活质量指标，保持她们的初始体重，并拥有更有利的雌激素代谢物特征。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The objectives of this pilot study are to; 1) quantify the effect of a 12 week home based walking intervention and a combined 12-week walking and diet intervention on physical activity levels, fitness, quality of life, body composition, and estrogen metabolism in survivors of breast cancer, and 2) develop and test the feasibility of physical activity and diet intervention materials for future studies in this population. We hypothesize that women randomized to the walking intervention will report higher levels of physical activity, and quality of life indicators for physical status, maintain their initial body weight, and have more favorable estrogen metabolite profiles.