HYPERTENSION, OXIDATIVE STRESS AND RACE

本子项目是利用由NIH/NCRR资助的中心赠款提供的资源的众多研究子项目之一。子项目和研究者（PI）可能已经从另一个NIH来源获得了主要资金，因此可以在其他CRISP条目中表示。列出的机构是中心的，不一定是研究者的机构。研究表明，高血压，也被称为高血压，在非裔美国人中比在白种人中更常见。因此，本研究将重点关注非裔美国人的高血压，并研究可能导致高血压在该人群中更常见的因素。在这项研究中要研究的因素是一种被称为氧化应激的状况。氧化应激是血液中产生过多氧气，细胞质量开始下降的一种情况。两种化学物质，如活性氧（ROS）和f2 -异前列腺素，在血液中含量过高时，会导致这种情况。这项研究的目的是测量这些化学物质，并确定患有高血压的非裔美国人是否比血压正常的人有更高的这些化学物质水平。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Studies show that hypertension, also known as high blood pressure, occurs more commonly in African-Americans than in Caucasians. For this reason, this study will focus on hypertension in African-Americans and examine factors that may cause hypertension to be found more often in this population. The factor that will be examined in this study is a condition known as oxidative stress. Oxidative stress is a condition where too much oxygen is produced in the blood and the cells begin to decline in quality. Two chemicals, such as, reactive oxygen species (ROS) and F2-isoprostane, when found in high levels in the blood, can cause this condition. The purpose of this study is to measure these chemicals and determine if African-Americans with high blood pressure have higher levels of these chemicals than in subjects with normal blood pressure readings.