BODY COMPOSITION

本子项目是利用由NIH/NCRR资助的中心赠款提供的资源的众多研究子项目之一。子项目和研究者（PI）可能已经从另一个NIH来源获得了主要资金，因此可以在其他CRISP条目中表示。列出的机构是中心的，不一定是研究者的机构。一项大型横断面研究显示，在夏威夷最大的夏威夷原住民社区（NH）的卫生保健中心，儿童超重的患病率非常高。这在新西兰和萨摩亚儿童中尤为明显。然而，这种高超重率的原因、意义和后果尚不清楚。年龄体重指数（BMI）百分位数高的儿童患成人肥胖和肥胖相关疾病的风险高。然而，由于没有对萨摩亚或新西兰儿童的身体成分进行研究，以确定高BMI的过度肥胖程度，因此尚不清楚他们的风险是否相似。一项关于体脂率（BF%）和身体质量指数之间关系的研究将有助于确定太平洋岛（PI）儿童的肥胖风险，特别是那些超重的儿童。研究报告称，波利尼西亚成年人在给定的体重指数下比白种人更瘦，这表明肥胖风险可能不同。本研究的总体目的是评估在不同PI种族的儿童中进行大型身体成分研究的可行性。具体目的是：1)研究萨摩亚、新西兰、菲律宾和高加索儿童在给定BMI下的无脂肪质量（FFM）和BF%之间的关系；2)开发评估入组、建立社区伙伴关系和招募参与者的机制；3)评估在后续更大规模研究中评估FFM和BF%所需的效应量。这项研究将是一项针对健康的5至9.9岁的新西兰、萨摩亚、菲律宾和高加索儿童的横断面研究。参与者将从瓦胡岛的怀阿纳社区招募，那里有一个大型萨摩亚社区和最大的NH社区。将使用脚对脚的生物电阻抗分析来确定无脂质量，并检查FFM， %BF和BMI之间的关系。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. A large cross-sectional study of children attending a health care center serving the largest community of Native Hawaiians (NH) in Hawaii showed a very high prevalence of overweight. This was especially pronounced in NH and Samoan children. The cause, significance and consequence of this high overweight prevalence, however, is unclear. Children with a high body mass index (BMI) percentile for age are at high risk for adult obesity and obesity related illness. However, because there are no body composition studies on Samoan or NH children defining the degree of excess adiposity at high BMI, it is not known if their risk is similar. A study examining the relationship between body fat percent (BF%) and BMI will help define the Pacific Island (PI) children at risk for obesity, especially those who are overweight. Studies have reported that Polynesian adults are leaner at a given BMI than Caucasians suggesting that obesity risk may be different. The overall aim of this study is to assess the feasibility of conducting a large body composition study on children of different PI ethnicities. The specific aims are 1) To examine the relationship between fat free mass (FFM) and BF% for a given BMI in Samoan, NH, Filipino and Caucasian children, 2) To develop mechanisms for estimating enrollment, creating community partnerships and recruiting participants, 3) To assess the effect size needed to assess FFM and BF% in a subsequent larger study. The study will be a cross sectional study on healthy NH, Samoan, Filipino and Caucasian children, 5 to 9.9 years of age. Participants will be recruited from the Waianae community of Oahu, home to a large Samoan community and the largest NH community. Fat free mass will be determined using foot-to-foot bioelectrical impedance analysis and the relationship between FFM, %BF and BMI examined.